{"id":9697,"date":"2026-09-12T22:07:05","date_gmt":"2026-09-12T22:07:05","guid":{"rendered":"https:\/\/kriyasya.com\/pulse\/?p=9697"},"modified":"2026-09-12T22:07:05","modified_gmt":"2026-09-12T22:07:05","slug":"ayurveda-punarnava-clinical-pharmacology","status":"publish","type":"post","link":"https:\/\/kriyasya.com\/pulse\/ayurveda-punarnava-clinical-pharmacology\/","title":{"rendered":"Punarnava&#8217;s Renal Alchemy: Restoring Tubular Fluid Balance and Shielding Kidneys"},"content":{"rendered":"<article>\n<p class=\"kr-lead-paragraph\">The subtle tension in the lower back, the tell-tale puffiness around the eyes, the persistent feeling of heaviness\u2014these are visceral signals of compromised renal function, often rooted in a disruption of the delicate tubular fluid balance. For millennia, Ayurvedic practitioners have turned to Punarnava (<em>Boerhavia diffusa<\/em>), a humble creeping plant, as a potent ally in restoring this equilibrium and safeguarding the kidneys.<\/p>\n<div class=\"kr-brief-takeaways\">\n<h3>Key Takeaways:<\/h3>\n<ul>\n<li>Punarnava&#8217;s classical efficacy in managing edema (<em>Shotha<\/em>) and urinary issues is supported by its ability to modulate renal tubular fluid reabsorption and excretion.<\/li>\n<li>Modern pharmacology identifies key alkaloids, particularly Punarnavine, as the primary drivers of its diuretic and nephroprotective actions.<\/li>\n<li>Mechanisms include inhibition of sodium-potassium ATPase, anti-inflammatory signaling via NF-\u03baB pathways, and potent antioxidant defense against oxidative stress in renal tissues.<\/li>\n<li>Clinical application involves careful formulation and dosage, often in combination with other herbs, tailored to individual constitutional types (Dosha).<\/li>\n<\/ul>\n<\/div>\n<div class=\"kr-brief-facts\">\n<h2>Fast Facts: Punarnava&#8217;s Renal Action<\/h2>\n<div class=\"kr-brief-fact-card\">\n<p class=\"metric\">~20%<\/p>\n<p class=\"label\">Diuretic Potency<\/p>\n<p class=\"subtext\">Significant increase in urine output observed in preclinical models, indicating enhanced glomerular filtration and reduced tubular reabsorption.<\/p>\n<\/p><\/div>\n<div class=\"kr-brief-fact-card\">\n<p class=\"metric\">10-fold<\/p>\n<p class=\"label\">Antioxidant Capacity<\/p>\n<p class=\"subtext\">Demonstrated free radical scavenging activity, protecting renal cells from damage induced by reactive oxygen species (ROS).<\/p>\n<\/p><\/div>\n<div class=\"kr-brief-fact-card\">\n<p class=\"metric\">50%<\/p>\n<p class=\"label\">Inflammation Reduction<\/p>\n<p class=\"subtext\">Inhibition of pro-inflammatory cytokines like TNF-\u03b1 and IL-6, crucial for preventing renal tissue damage.<\/p>\n<\/p><\/div>\n<\/div>\n<h2 class=\"wp-block-heading\">The Ayurvedic Framework: Restoring Equilibrium<\/h2>\n<p>Ayurveda posits that kidney dysfunction, particularly conditions manifesting as edema (<em>Shotha<\/em>) and urinary anomalies, arises from an imbalance of the Doshas, primarily Kapha and Vata, leading to impaired <em>Apana Vayu<\/em> and accumulation of <em>Ama<\/em> (metabolic toxins). The <em>Mootravaha Srotas<\/em> (channels of urine elimination) become obstructed. Punarnava, classically described as having <em>Kashaya-Madhura Rasa<\/em> (astringent-sweet taste), <em>Laghu-Ruksha Guna<\/em> (light-dry qualities), and a <em>Vipaka<\/em> (post-digestive effect) that is <em>Madhura<\/em> (sweet), is considered a potent <em>Mutral<\/em> (diuretic) and <em>Shothahara<\/em> (anti-edema) herb.<\/p>\n<p>Classical texts like the <strong>Charaka Samhita<\/strong> (Sutrasthana, Chapter 27) and <strong>Sushruta Samhita<\/strong> (Uttara Tantra, Chapter 45) detail its use in managing dropsy and urinary calculus. The <strong>Brihat Nighantu Ratnakara<\/strong> further elaborates on its properties, highlighting its ability to pacify Kapha and Vata, thereby clearing the channels and promoting the excretion of excess fluid and toxins.<\/p>\n<h2 class=\"wp-block-heading\">Modern Pharmacology: Unraveling the Molecular Mechanisms<\/h2>\n<p>Contemporary research validates and elucidates the ancient observations. The primary active constituents of <em>Boerhavia diffusa<\/em> are its alkaloids, notably Punarnavine, along with other compounds like hypaphorine, umbelliferone, and flavonoids. Punarnavine, in particular, has been the focus of extensive pharmacological investigation.<\/p>\n<p><strong>Diuretic Action:<\/strong> Studies indicate that Punarnavine acts by inhibiting the Na+\/K+-ATPase enzyme system in the renal tubules. This inhibition reduces sodium and potassium reabsorption, leading to increased osmotic pressure within the tubules and consequently, enhanced water excretion. This mechanism directly addresses the tubular fluid imbalance, promoting diuresis without significant electrolyte loss, a key differentiator from synthetic diuretics. (<em>Joshi et al., 2013; Kumar et al., 2010<\/em>).<\/p>\n<p><strong>Nephroprotection:<\/strong> Punarnava exhibits robust nephroprotective effects through multiple pathways:<\/p>\n<ul>\n<li><strong>Anti-inflammatory:<\/strong> It significantly downregulates the Nuclear Factor-kappa B (NF-\u03baB) signaling pathway, a master regulator of inflammation. By inhibiting NF-\u03baB activation, Punarnava reduces the production of pro-inflammatory cytokines such as Tumor Necrosis Factor-alpha (TNF-\u03b1) and Interleukin-6 (IL-6), which are implicated in the pathogenesis of various kidney diseases. (<em>Kavitha et al., 2012<\/em>).<\/li>\n<li><strong>Antioxidant:<\/strong> The herb possesses potent free radical scavenging activity. It enhances the levels of endogenous antioxidant enzymes like superoxide dismutase (SOD) and catalase, while reducing lipid peroxidation, thereby protecting renal cells from oxidative stress induced by toxins, ischemia-reperfusion injury, or underlying disease processes. (<em>Saha et al., 2015<\/em>).<\/li>\n<li><strong>Hepatoprotective Synergy:<\/strong> Given the close functional and anatomical relationship between the liver and kidneys in detoxification (as per Ayurveda&#8217;s concept of interconnected <em>Srotas<\/em>), Punarnava&#8217;s known hepatoprotective properties indirectly support renal health by improving overall detoxification capacity.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Clinical Application and Integration<\/h2>\n<p>In Ayurvedic practice, Punarnava is rarely used in isolation. It is often incorporated into complex formulations like Punarnavadi Kashayam or Punarnavadi Guggulu, where its properties are synergistically enhanced by other herbs such as Ginger (<em>Shunthi<\/em>), Black Pepper (<em>Maricha<\/em>), Long Pepper (<em>Pippali<\/em>), Turmeric (<em>Haridra<\/em>), and Triphala. This polyherbal approach aims to address the multifactorial nature of renal disorders and individual constitutional needs (Prakriti).<\/p>\n<p>The dosage and preparation are meticulously determined based on the patient&#8217;s Dosha imbalance, the severity of the condition, and the presence of other comorbidities. For instance, in a Kapha-dominant presentation with significant edema, a decoction (Kashayam) might be preferred for its lighter, quicker action. In cases involving Vata vitiation and pain, formulations incorporating Guggulu might be chosen for their deeper tissue penetration and anti-inflammatory effects.<\/p>\n<div class=\"kr-protocol-box\">\n<h3>Punarnava Renal Support Protocol (Illustrative)<\/h3>\n<ol>\n<li><strong>Assessment:<\/strong> Determine individual Prakriti and Vikriti (constitutional type and current imbalance) using Ayurvedic principles. Assess renal function markers (e.g., GFR, creatinine, BUN) and fluid balance status (edema, urine output).<\/li>\n<li><strong>Herbal Selection:<\/strong> Based on assessment, select appropriate Punarnava formulation (e.g., Punarnavadi Kashayam, Punarnavadi Guggulu, or standardized Punarnava extract). Consider synergistic herbs based on specific symptoms and Dosha involvement.<\/li>\n<li><strong>Dosage &amp; Administration:<\/strong> Administer the chosen formulation at a dose determined by an experienced Ayurvedic practitioner, typically ranging from 10-30 ml of Kashayam or 1-2 Guggulu tablets twice daily, usually before meals. Adjust based on response.<\/li>\n<li><strong>Dietary &amp; Lifestyle Modifications:<\/strong> Recommend a diet low in salt and processed foods, emphasizing fresh, easily digestible foods. Encourage adequate hydration (unless contraindicated) and regular, moderate exercise. Avoid Vata-aggravating factors.<\/li>\n<li><strong>Monitoring:<\/strong> Regularly monitor urine output, edema levels, and relevant biochemical parameters. Adjust treatment as needed.<\/li>\n<\/ol>\n<p><em>Note: This is a general guideline. Always consult a qualified Ayurvedic physician for personalized treatment.<\/em><\/p>\n<\/div>\n<div class=\"kr-calc-embed-callout\">\n<p>Curious about your unique Ayurvedic constitution? Understanding your Prakriti can guide personalized wellness strategies. <a href=\"\/calculators\/dosha-diagnostic\/\" target=\"_blank\">Take the Ayurvedic Dosha Diagnostic Quiz now.<\/a><\/p>\n<\/div>\n<div class=\"kr-brief-sources\">\n<h3>References<\/h3>\n<ul>\n<li>Charaka Samhita, Sutrasthana, Chapter 27.<\/li>\n<li>Sushruta Samhita, Uttara Tantra, Chapter 45.<\/li>\n<li>Brihat Nighantu Ratnakara.<\/li>\n<li>Joshi, R., et al. (2013). Pharmacological activities of Boerhavia diffusa: A review. <em>International Journal of Pharmaceutical Sciences and Research<\/em>, 4(11), 4101-4110.<\/li>\n<li>Kumar, V., et al. (2010). Diuretic and anti-inflammatory activity of Boerhavia diffusa root. <em>Journal of Ethnopharmacology<\/em>, 128(2), 435-439.<\/li>\n<li>Kavitha, K., et al. (2012). Anti-inflammatory and antioxidant potential of Boerhavia diffusa Linn. in experimental models. <em>Journal of Ethnopharmacology<\/em>, 143(1), 320-326.<\/li>\n<li>Saha, S., et al. (2015). Antioxidant and nephroprotective effects of Boerhavia diffusa extract against cisplatin-induced renal toxicity. <em>Journal of Complementary and Integrative Medicine<\/em>, 12(2), 139-147.<\/li>\n<\/ul>\n<\/div>\n<\/article>\n","protected":false},"excerpt":{"rendered":"<p>Discover how Punarnava (Boerhavia diffusa), a cornerstone of Ayurvedic renal therapy, precisely modulates kidney fluid balance and offers profound nephroprotection through ancient wisdom and modern molecular mechanisms.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_kr_title_hi":"\u092a\u0941\u0928\u0930\u094d\u0928\u0935\u093e: \u0917\u0941\u0930\u094d\u0926\u094b\u0902 \u0915\u0947 \u0932\u093f\u090f \u0906\u092f\u0941\u0930\u094d\u0935\u0947\u0926 \u0915\u093e \u0905\u092e\u0943\u0924, \u0924\u0930\u0932 \u0938\u0902\u0924\u0941\u0932\u0928 \u092c\u0939\u093e\u0932 \u0915\u0930\u0947 \u0914\u0930 \u0938\u0941\u0930\u0915\u094d\u0937\u093e \u092a\u094d\u0930\u0926\u093e\u0928 \u0915\u0930\u0947","_kr_excerpt_hi":"\u091c\u093e\u0928\u0947\u0902 \u0915\u0948\u0938\u0947 \u092a\u0941\u0928\u0930\u094d\u0928\u0935\u093e (\u092d\u094b\u0930\u0939\u0935\u093f\u092f\u093e \u0921\u093f\u092b\u094d\u092f\u0942\u0938\u093e), \u0906\u092f\u0941\u0930\u094d\u0935\u0947\u0926 \u0915\u0940 \u0917\u0941\u0930\u094d\u0926\u093e \u091a\u093f\u0915\u093f\u0924\u094d\u0938\u093e \u0915\u093e \u090f\u0915 \u092a\u094d\u0930\u092e\u0941\u0916 \u0938\u094d\u0924\u0902\u092d, \u092a\u094d\u0930\u093e\u091a\u0940\u0928 \u091c\u094d\u091e\u093e\u0928 \u0914\u0930 \u0906\u0927\u0941\u0928\u093f\u0915 \u0906\u0923\u0935\u093f\u0915 \u0924\u0902\u0924\u094d\u0930 \u0915\u0947 \u092e\u093e\u0927\u094d\u092f\u092e \u0938\u0947 \u0917\u0941\u0930\u094d\u0926\u094b\u0902 \u0915\u0947 \u0924\u0930\u0932 \u0938\u0902\u0924\u0941\u0932\u0928 \u0915\u094b \u0928\u093f\u092f\u0902\u0924\u094d\u0930\u093f\u0924 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\u092a\u094d\u0930\u0915\u093e\u0930\u094b\u0902 (\u0926\u094b\u0937) \u0915\u0947 \u0905\u0928\u0941\u0930\u0942\u092a\u0964<\/li>\n  <\/ul>\n<\/div>\n\n<div class=\"kr-brief-facts\">\n  <h2>\u0938\u0902\u0915\u094d\u0937\u093f\u092a\u094d\u0924 \u0924\u0925\u094d\u092f: \u092a\u0941\u0928\u0930\u094d\u0928\u0935\u093e \u0915\u0940 \u0917\u0941\u0930\u094d\u0926\u093e \u0915\u094d\u0930\u093f\u092f\u093e<\/h2>\n  <div class=\"kr-brief-fact-card\">\n    <p class=\"metric\">~20%<\/p>\n    <p class=\"label\">\u092e\u0942\u0924\u094d\u0930\u0935\u0930\u094d\u0927\u0915 \u0915\u094d\u0937\u092e\u0924\u093e<\/p>\n    <p class=\"subtext\">\u092a\u0942\u0930\u094d\u0935-\u0928\u0948\u0926\u093e\u0928\u093f\u0915 \u200b\u200b\u092e\u0949\u0921\u0932 \u092e\u0947\u0902 \u092e\u0942\u0924\u094d\u0930 \u0909\u0924\u094d\u092a\u093e\u0926\u0928 \u092e\u0947\u0902 \u0909\u0932\u094d\u0932\u0947\u0916\u0928\u0940\u092f \u0935\u0943\u0926\u094d\u0927\u093f \u0926\u0947\u0916\u0940 \u0917\u0908, \u091c\u094b \u092c\u0922\u093c\u0940 \u0939\u0941\u0908 \u0917\u094d\u0932\u094b\u092e\u0947\u0930\u0941\u0932\u0930 \u0928\u093f\u0938\u094d\u092a\u0902\u0926\u0928 \u0914\u0930 \u0915\u092e \u091f\u094d\u092f\u0942\u092c\u0932\u0930 \u092a\u0941\u0928: \u0905\u0935\u0936\u094b\u0937\u0923 \u0915\u093e \u0938\u0902\u0915\u0947\u0924 \u0926\u0947\u0924\u0940 \u0939\u0948\u0964<\/p>\n  <\/div>\n  <div class=\"kr-brief-fact-card\">\n    <p class=\"metric\">10 \u0917\u0941\u0928\u093e<\/p>\n    <p class=\"label\">\u090f\u0902\u091f\u0940\u0911\u0915\u094d\u0938\u0940\u0921\u0947\u0902\u091f \u0915\u094d\u0937\u092e\u0924\u093e<\/p>\n    <p class=\"subtext\">\u092e\u0941\u0915\u094d\u0924 \u0915\u0923\u094b\u0902 \u0915\u094b \u0938\u093e\u092b \u0915\u0930\u0928\u0947 \u0915\u0940 \u092a\u094d\u0930\u0926\u0930\u094d\u0936\u093f\u0924 \u0917\u0924\u093f\u0935\u093f\u0927\u093f, \u0917\u0941\u0930\u094d\u0926\u0947 \u0915\u0940 \u0915\u094b\u0936\u093f\u0915\u093e\u0913\u0902 \u0915\u094b \u092a\u094d\u0930\u0924\u093f\u0915\u094d\u0930\u093f\u092f\u093e\u0936\u0940\u0932 \u0911\u0915\u094d\u0938\u0940\u091c\u0928 \u092a\u094d\u0930\u091c\u093e\u0924\u093f\u092f\u094b\u0902 (ROS) \u0926\u094d\u0935\u093e\u0930\u093e \u092a\u094d\u0930\u0947\u0930\u093f\u0924 \u0915\u094d\u0937\u0924\u093f \u0938\u0947 \u092c\u091a\u093e\u0924\u0940 \u0939\u0948\u0964<\/p>\n  <\/div>\n  <div class=\"kr-brief-fact-card\">\n    <p class=\"metric\">50%<\/p>\n    <p class=\"label\">\u0938\u0942\u091c\u0928 \u092e\u0947\u0902 \u0915\u092e\u0940<\/p>\n    <p class=\"subtext\">TNF-\u03b1 \u0914\u0930 IL-6 \u091c\u0948\u0938\u0947 \u0938\u0942\u091c\u0928-\u0930\u094b\u0927\u0940 \u0938\u093e\u0907\u091f\u094b\u0915\u093f\u0928\u094d\u0938 \u0915\u093e \u0905\u0935\u0930\u094b\u0927, \u0917\u0941\u0930\u094d\u0926\u0947 \u0915\u0947 \u090a\u0924\u0915\u094b\u0902 \u0915\u094b \u0928\u0941\u0915\u0938\u093e\u0928 \u0915\u094b \u0930\u094b\u0915\u0928\u0947 \u0915\u0947 \u0932\u093f\u090f \u092e\u0939\u0924\u094d\u0935\u092a\u0942\u0930\u094d\u0923 \u0939\u0948\u0964<\/p>\n  <\/div>\n<\/div>\n\n<h2 class=\"wp-block-heading\">\u0906\u092f\u0941\u0930\u094d\u0935\u0947\u0926\u093f\u0915 \u0922\u093e\u0901\u091a\u093e: \u0938\u0902\u0924\u0941\u0932\u0928 \u092c\u0939\u093e\u0932 \u0915\u0930\u0928\u093e<\/h2>\n<p>\u0906\u092f\u0941\u0930\u094d\u0935\u0947\u0926 \u092e\u093e\u0928\u0924\u093e \u0939\u0948 \u0915\u093f \u0917\u0941\u0930\u094d\u0926\u0947 \u0915\u0940 \u0936\u093f\u0925\u093f\u0932\u0924\u093e, \u0935\u093f\u0936\u0947\u0937 \u0930\u0942\u092a \u0938\u0947 \u090f\u0921\u093f\u092e\u093e (<em>\u0936\u094b\u0925<\/em>) \u0914\u0930 \u092e\u0942\u0924\u094d\u0930 \u0938\u0902\u092c\u0902\u0927\u0940 \u0935\u093f\u0938\u0902\u0917\u0924\u093f\u092f\u094b\u0902 \u0915\u0947 \u0930\u0942\u092a \u092e\u0947\u0902 \u092a\u094d\u0930\u0915\u091f \u0939\u094b\u0928\u0947 \u0935\u093e\u0932\u0940 \u0938\u094d\u0925\u093f\u0924\u093f\u092f\u093e\u0901, \u0926\u094b\u0937\u094b\u0902, \u092e\u0941\u0916\u094d\u092f \u0930\u0942\u092a \u0938\u0947 \u0915\u092b \u0914\u0930 \u0935\u093e\u0924 \u0915\u0947 \u0905\u0938\u0902\u0924\u0941\u0932\u0928 \u0938\u0947 \u0909\u0924\u094d\u092a\u0928\u094d\u0928 \u0939\u094b\u0924\u0940 \u0939\u0948\u0902, \u091c\u093f\u0938\u0938\u0947 <em>\u0905\u092a\u093e\u0928 \u0935\u093e\u092f\u0941<\/em> \u0915\u093e \u0915\u094d\u0937\u0930\u0923 \u0939\u094b\u0924\u093e \u0939\u0948 \u0914\u0930 <em>\u0906\u092e<\/em> (\u091a\u092f\u093e\u092a\u091a\u092f \u0935\u093f\u0937\u093e\u0915\u094d\u0924 \u092a\u0926\u093e\u0930\u094d\u0925) \u0915\u093e \u0938\u0902\u091a\u092f \u0939\u094b\u0924\u093e \u0939\u0948\u0964 <em>\u092e\u0942\u0924\u094d\u0930\u0935\u093e\u0939\u093f\u0928\u0940 \u0938\u094d\u0930\u094b\u0924\u0938<\/em> (\u092e\u0942\u0924\u094d\u0930 \u0909\u0924\u094d\u0938\u0930\u094d\u091c\u0928 \u0915\u0947 \u091a\u0948\u0928\u0932) \u0905\u0935\u0930\u0941\u0926\u094d\u0927 \u0939\u094b \u091c\u093e\u0924\u0947 \u0939\u0948\u0902\u0964 \u092a\u0941\u0928\u0930\u094d\u0928\u0935\u093e, \u091c\u093f\u0938\u0947 \u0936\u093e\u0938\u094d\u0924\u094d\u0930\u0940\u092f \u0930\u0942\u092a \u0938\u0947 <em>\u0915\u0937\u093e\u092f-\u092e\u0927\u0941\u0930 \u0930\u0938<\/em> (\u0915\u0921\u093c\u0935\u093e-\u092e\u0940\u0920\u093e \u0938\u094d\u0935\u093e\u0926), <em>\u0932\u0918\u0941-\u0930\u0941\u0915\u094d\u0937 \u0917\u0941\u0923<\/em> (\u0939\u0932\u094d\u0915\u0947-\u0938\u0942\u0916\u0947 \u0917\u0941\u0923), \u0914\u0930 \u090f\u0915 <em>\u0935\u093f\u092a\u093e\u0915<\/em> (\u092a\u093e\u091a\u0928 \u0915\u0947 \u092c\u093e\u0926 \u0915\u093e \u092a\u094d\u0930\u092d\u093e\u0935) \u091c\u094b <em>\u092e\u0927\u0941\u0930<\/em> (\u092e\u0940\u0920\u093e) \u0939\u0948, \u092e\u093e\u0928\u093e \u091c\u093e\u0924\u093e \u0939\u0948, \u090f\u0915 \u0936\u0915\u094d\u0924\u093f\u0936\u093e\u0932\u0940 <em>\u092e\u0942\u0924\u094d\u0930\u0932<\/em> (\u092e\u0942\u0924\u094d\u0930\u0935\u0930\u094d\u0927\u0915) \u0914\u0930 <em>\u0936\u094b\u0925\u0939\u0930<\/em> (\u0938\u0942\u091c\u0928-\u0930\u094b\u0927\u0940) \u091c\u0921\u093c\u0940 \u092c\u0942\u091f\u0940 \u0939\u0948\u0964<\/p>\n<p><strong>\u091a\u0930\u0915 \u0938\u0902\u0939\u093f\u0924\u093e<\/strong> (\u0938\u0942\u0924\u094d\u0930\u0938\u094d\u0925\u093e\u0928, \u0905\u0927\u094d\u092f\u093e\u092f 27) \u0914\u0930 <strong>\u0938\u0941\u0936\u094d\u0930\u0941\u0924 \u0938\u0902\u0939\u093f\u0924\u093e<\/strong> (\u0909\u0924\u094d\u0924\u0930 \u0924\u0902\u0924\u094d\u0930, \u0905\u0927\u094d\u092f\u093e\u092f 45) \u091c\u0948\u0938\u0947 \u0936\u093e\u0938\u094d\u0924\u094d\u0930\u0940\u092f \u0917\u094d\u0930\u0902\u0925 \u091c\u0932\u094b\u0926\u0930 \u0914\u0930 \u0917\u0941\u0930\u094d\u0926\u0947 \u0915\u0940 \u092a\u0925\u0930\u0940 \u0915\u0947 \u092a\u094d\u0930\u092c\u0902\u0927\u0928 \u092e\u0947\u0902 \u0907\u0938\u0915\u0947 \u0909\u092a\u092f\u094b\u0917 \u0915\u093e \u0935\u093f\u0935\u0930\u0923 \u0926\u0947\u0924\u0947 \u0939\u0948\u0902\u0964 <strong>\u092c\u0943\u0939\u0924\u094d \u0928\u093f\u0918\u0902\u091f\u0941 \u0930\u0924\u094d\u0928\u093e\u0915\u0930<\/strong> \u0907\u0938\u0915\u0947 \u0917\u0941\u0923\u094b\u0902 \u092a\u0930 \u0914\u0930 \u0935\u093f\u0938\u094d\u0924\u093e\u0930 \u0938\u0947 \u092c\u0924\u093e\u0924\u093e \u0939\u0948, \u0915\u092b \u0914\u0930 \u0935\u093e\u0924 \u0915\u094b \u0936\u093e\u0902\u0924 \u0915\u0930\u0928\u0947 \u0915\u0940 \u0907\u0938\u0915\u0940 \u0915\u094d\u0937\u092e\u0924\u093e \u092a\u0930 \u092a\u094d\u0930\u0915\u093e\u0936 \u0921\u093e\u0932\u0924\u093e \u0939\u0948, \u091c\u093f\u0938\u0938\u0947 \u091a\u0948\u0928\u0932 \u0938\u093e\u092b \u0939\u094b\u0924\u0947 \u0939\u0948\u0902 \u0914\u0930 \u0905\u0924\u093f\u0930\u093f\u0915\u094d\u0924 \u0926\u094d\u0930\u0935 \u0914\u0930 \u0935\u093f\u0937\u093e\u0915\u094d\u0924 \u092a\u0926\u093e\u0930\u094d\u0925\u094b\u0902 \u0915\u093e \u0909\u0924\u094d\u0938\u0930\u094d\u091c\u0928 \u092c\u0922\u093c\u093e\u0935\u093e \u092e\u093f\u0932\u0924\u093e \u0939\u0948\u0964<\/p>\n\n<h2 class=\"wp-block-heading\">\u0906\u0927\u0941\u0928\u093f\u0915 \u0914\u0937\u0927 \u0935\u093f\u091c\u094d\u091e\u093e\u0928: \u0906\u0923\u0935\u093f\u0915 \u0924\u0902\u0924\u094d\u0930 \u0915\u094b \u0909\u091c\u093e\u0917\u0930 \u0915\u0930\u0928\u093e<\/h2>\n<p>\u0938\u092e\u0915\u093e\u0932\u0940\u0928 \u0905\u0928\u0941\u0938\u0902\u0927\u093e\u0928 \u092a\u094d\u0930\u093e\u091a\u0940\u0928 \u0905\u0935\u0932\u094b\u0915\u0928\u094b\u0902 \u0915\u094b \u092e\u093e\u0928\u094d\u092f \u0914\u0930 \u0938\u094d\u092a\u0937\u094d\u091f \u0915\u0930\u0924\u093e \u0939\u0948\u0964 <em>\u092d\u094b\u0930\u0939\u0935\u093f\u092f\u093e \u0921\u093f\u092b\u094d\u092f\u0942\u0938\u093e<\/em> \u0915\u0947 \u092a\u094d\u0930\u093e\u0925\u092e\u093f\u0915 \u0938\u0915\u094d\u0930\u093f\u092f \u0918\u091f\u0915 \u0907\u0938\u0915\u0947 \u090f\u0932\u094d\u0915\u0932\u0949\u0907\u0921\u094d\u0938 \u0939\u0948\u0902, \u0935\u093f\u0936\u0947\u0937 \u0930\u0942\u092a \u0938\u0947 \u092a\u0941\u0928\u0930\u094d\u0928\u0935\u093f\u0928, \u0938\u093e\u0925 \u0939\u0940 \u0939\u093e\u0907\u092a\u094b\u092b\u094b\u0930\u093f\u0928, \u0905\u092e\u094d\u092c\u0947\u0932\u0940\u092b\u0947\u0930\u094b\u0928 \u0914\u0930 \u092b\u094d\u0932\u0947\u0935\u094b\u0928\u094b\u0907\u0921\u094d\u0938 \u091c\u0948\u0938\u0947 \u0905\u0928\u094d\u092f \u092f\u094c\u0917\u093f\u0915\u0964 \u0935\u093f\u0936\u0947\u0937 \u0930\u0942\u092a \u0938\u0947 \u092a\u0941\u0928\u0930\u094d\u0928\u0935\u093f\u0928, \u0935\u094d\u092f\u093e\u092a\u0915 \u0914\u0937\u0927\u0940\u092f \u091c\u093e\u0902\u091a \u0915\u093e \u0915\u0947\u0902\u0926\u094d\u0930 \u0930\u0939\u093e \u0939\u0948\u0964<\/p>\n<p><strong>\u092e\u0942\u0924\u094d\u0930\u0935\u0930\u094d\u0927\u0915 \u0915\u094d\u0930\u093f\u092f\u093e:<\/strong> \u0905\u0927\u094d\u092f\u092f\u0928\u094b\u0902 \u0938\u0947 \u092a\u0924\u093e \u091a\u0932\u0924\u093e \u0939\u0948 \u0915\u093f \u092a\u0941\u0928\u0930\u094d\u0928\u0935\u093f\u0928 \u0917\u0941\u0930\u094d\u0926\u0947 \u0915\u0940 \u0928\u0932\u093f\u0915\u093e\u0913\u0902 \u092e\u0947\u0902 Na+\/K+-ATPase \u090f\u0902\u091c\u093e\u0907\u092e \u092a\u094d\u0930\u0923\u093e\u0932\u0940 \u0915\u094b \u092c\u093e\u0927\u093f\u0924 \u0915\u0930\u0915\u0947 \u0915\u093e\u0930\u094d\u092f \u0915\u0930\u0924\u093e \u0939\u0948\u0964 \u092f\u0939 \u0905\u0935\u0930\u094b\u0927 \u0938\u094b\u0921\u093f\u092f\u092e \u0914\u0930 \u092a\u094b\u091f\u0947\u0936\u093f\u092f\u092e \u0915\u0947 \u092a\u0941\u0928: \u0905\u0935\u0936\u094b\u0937\u0923 \u0915\u094b \u0915\u092e \u0915\u0930\u0924\u093e \u0939\u0948, \u091c\u093f\u0938\u0938\u0947 \u0928\u0932\u093f\u0915\u093e\u0913\u0902 \u0915\u0947 \u092d\u0940\u0924\u0930 \u0911\u0938\u094d\u092e\u094b\u091f\u093f\u0915 \u0926\u092c\u093e\u0935 \u092c\u0922\u093c \u091c\u093e\u0924\u093e \u0939\u0948 \u0914\u0930 \u092a\u0930\u093f\u0923\u093e\u092e\u0938\u094d\u0935\u0930\u0942\u092a, \u092a\u093e\u0928\u0940 \u0915\u093e \u0909\u0924\u094d\u0938\u0930\u094d\u091c\u0928 \u092c\u0922\u093c \u091c\u093e\u0924\u093e \u0939\u0948\u0964 \u092f\u0939 \u0924\u0902\u0924\u094d\u0930 \u0938\u0940\u0927\u0947 \u091f\u094d\u092f\u0942\u092c\u0941\u0932\u0930 \u0926\u094d\u0930\u0935 \u0905\u0938\u0902\u0924\u0941\u0932\u0928 \u0915\u094b \u0938\u0902\u092c\u094b\u0927\u093f\u0924 \u0915\u0930\u0924\u093e \u0939\u0948, \u0938\u093f\u0902\u0925\u0947\u091f\u093f\u0915 \u092e\u0942\u0924\u094d\u0930\u0935\u0930\u094d\u0927\u0915\u094b\u0902 \u0938\u0947 \u090f\u0915 \u092a\u094d\u0930\u092e\u0941\u0916 \u0905\u0902\u0924\u0930, \u092e\u0939\u0924\u094d\u0935\u092a\u0942\u0930\u094d\u0923 \u0907\u0932\u0947\u0915\u094d\u091f\u094d\u0930\u094b\u0932\u093e\u0907\u091f \u0939\u093e\u0928\u093f \u0915\u0947 \u092c\u093f\u0928\u093e \u092e\u0942\u0924\u094d\u0930\u0935\u0930\u094d\u0927 \u0915\u094b \u092c\u0922\u093c\u093e\u0935\u093e \u0926\u0947\u0924\u093e \u0939\u0948\u0964 (<em>\u091c\u094b\u0936\u0940 \u090f\u091f \u0905\u0932., 2013; \u0915\u0941\u092e\u093e\u0930 \u090f\u091f \u0905\u0932., 2010<\/em>)\u0964<\/p>\n<p><strong>\u0917\u0941\u0930\u094d\u0926\u093e \u0938\u0902\u0930\u0915\u094d\u0937\u0923:<\/strong> \u092a\u0941\u0928\u0930\u094d\u0928\u0935\u093e \u0915\u0908 \u092e\u093e\u0930\u094d\u0917\u094b\u0902 \u0938\u0947 \u092e\u091c\u092c\u0942\u0924 \u0917\u0941\u0930\u094d\u0926\u093e-\u0938\u0941\u0930\u0915\u094d\u0937\u093e\u0924\u094d\u092e\u0915 \u092a\u094d\u0930\u092d\u093e\u0935 \u092a\u094d\u0930\u0926\u0930\u094d\u0936\u093f\u0924 \u0915\u0930\u0924\u093e \u0939\u0948:<\/p>\n<ul>\n  <li><strong>\u0938\u0942\u091c\u0928-\u0930\u094b\u0927\u0940:<\/strong> \u092f\u0939 \u0928\u094d\u092f\u0942\u0915\u094d\u0932\u093f\u092f\u0930 \u092b\u0948\u0915\u094d\u091f\u0930-\u0915\u092a\u094d\u092a\u093e \u092c\u0940 (NF-\u03baB) \u0938\u093f\u0917\u094d\u0928\u0932\u093f\u0902\u0917 \u092a\u093e\u0925\u0935\u0947 \u0915\u094b \u092e\u0939\u0924\u094d\u0935\u092a\u0942\u0930\u094d\u0923 \u0930\u0942\u092a \u0938\u0947 \u0921\u093e\u0909\u0928-\u0930\u0947\u0917\u0941\u0932\u0947\u091f \u0915\u0930\u0924\u093e \u0939\u0948, \u091c\u094b \u0938\u0942\u091c\u0928 \u0915\u093e \u090f\u0915 \u092e\u093e\u0938\u094d\u091f\u0930 \u0930\u0947\u0917\u0941\u0932\u0947\u091f\u0930 \u0939\u0948\u0964 NF-\u03baB \u0938\u0915\u094d\u0930\u093f\u092f\u0923 \u0915\u094b \u092c\u093e\u0927\u093f\u0924 \u0915\u0930\u0915\u0947, \u092a\u0941\u0928\u0930\u094d\u0928\u0935\u093e \u091f\u094d\u092f\u0942\u092e\u0930 \u0928\u0947\u0915\u094d\u0930\u094b\u0938\u093f\u0938 \u092b\u0948\u0915\u094d\u091f\u0930-\u0905\u0932\u094d\u092b\u093e (TNF-\u03b1) \u0914\u0930 \u0907\u0902\u091f\u0930\u0932\u094d\u092f\u0942\u0915\u093f\u0928-6 (IL-6) \u091c\u0948\u0938\u0947 \u0938\u0942\u091c\u0928-\u0930\u094b\u0927\u0940 \u0938\u093e\u0907\u091f\u094b\u0915\u093f\u0928\u094d\u0938 \u0915\u0947 \u0909\u0924\u094d\u092a\u093e\u0926\u0928 \u0915\u094b \u0915\u092e \u0915\u0930\u0924\u093e \u0939\u0948, \u091c\u094b \u0935\u093f\u092d\u093f\u0928\u094d\u0928 \u0917\u0941\u0930\u094d\u0926\u0947 \u0915\u0940 \u092c\u0940\u092e\u093e\u0930\u093f\u092f\u094b\u0902 \u0915\u0947 \u0930\u094b\u0917\u091c\u0928\u0928 \u092e\u0947\u0902 \u0936\u093e\u092e\u093f\u0932 \u0939\u0948\u0902\u0964 (<em>\u0915\u0935\u093f\u0924\u093e \u090f\u091f \u0905\u0932., 2012<\/em>)\u0964<\/li>\n  <li><strong>\u090f\u0902\u091f\u0940\u0911\u0915\u094d\u0938\u0940\u0921\u0947\u0902\u091f:<\/strong> \u091c\u0921\u093c\u0940 \u092c\u0942\u091f\u0940 \u092e\u0947\u0902 \u0936\u0915\u094d\u0924\u093f\u0936\u093e\u0932\u0940 \u092e\u0941\u0915\u094d\u0924 \u0915\u0923\u094b\u0902 \u0915\u094b \u0938\u093e\u092b \u0915\u0930\u0928\u0947 \u0915\u0940 \u0917\u0924\u093f\u0935\u093f\u0927\u093f \u0939\u094b\u0924\u0940 \u0939\u0948\u0964 \u092f\u0939 \u0938\u0941\u092a\u0930\u0911\u0915\u094d\u0938\u093e\u0907\u0921 \u0921\u093f\u0938\u092e\u094d\u092f\u0942\u091f\u0947\u0938 (SOD) \u0914\u0930 \u0915\u0948\u091f\u093e\u0932\u0947\u091c \u091c\u0948\u0938\u0947 \u0905\u0902\u0924\u0930\u094d\u091c\u093e\u0924 \u090f\u0902\u091f\u0940\u0911\u0915\u094d\u0938\u0940\u0921\u0947\u0902\u091f \u090f\u0902\u091c\u093e\u0907\u092e\u094b\u0902 \u0915\u0947 \u0938\u094d\u0924\u0930 \u0915\u094b \u092c\u0922\u093c\u093e\u0924\u093e \u0939\u0948, \u091c\u092c\u0915\u093f \u0932\u093f\u092a\u093f\u0921 \u092a\u0947\u0930\u094b\u0915\u094d\u0938\u0940\u0921\u0947\u0936\u0928 \u0915\u094b \u0915\u092e \u0915\u0930\u0924\u093e \u0939\u0948, \u091c\u093f\u0938\u0938\u0947 \u0917\u0941\u0930\u094d\u0926\u0947 \u0915\u0940 \u0915\u094b\u0936\u093f\u0915\u093e\u090f\u0902 \u0935\u093f\u0937\u093e\u0915\u094d\u0924 \u092a\u0926\u093e\u0930\u094d\u0925\u094b\u0902, \u0907\u0938\u094d\u0915\u093f\u092e\u093f\u092f\u093e-\u0930\u093f\u092a\u0930\u092b\u094d\u092f\u0942\u091c\u0928 \u091a\u094b\u091f, \u092f\u093e \u0905\u0902\u0924\u0930\u094d\u0928\u093f\u0939\u093f\u0924 \u0930\u094b\u0917 \u092a\u094d\u0930\u0915\u094d\u0930\u093f\u092f\u093e\u0913\u0902 \u0926\u094d\u0935\u093e\u0930\u093e \u092a\u094d\u0930\u0947\u0930\u093f\u0924 \u0911\u0915\u094d\u0938\u0940\u0921\u0947\u091f\u093f\u0935 \u0924\u0928\u093e\u0935 \u0938\u0947 \u0938\u0941\u0930\u0915\u094d\u0937\u093f\u0924 \u0930\u0939\u0924\u0940 \u0939\u0948\u0902\u0964 (<em>\u0938\u093e\u0939\u093e \u090f\u091f \u0905\u0932., 2015<\/em>)\u0964<\/li>\n  <li><strong>\u092f\u0915\u0943\u0924-\u0938\u0941\u0930\u0915\u094d\u0937\u093e\u0924\u094d\u092e\u0915 \u0924\u093e\u0932\u092e\u0947\u0932:<\/strong> \u0935\u093f\u0937\u0939\u0930\u0923 \u092e\u0947\u0902 \u092f\u0915\u0943\u0924 \u0914\u0930 \u0917\u0941\u0930\u094d\u0926\u0947 \u0915\u0947 \u092c\u0940\u091a \u0918\u0928\u093f\u0937\u094d\u0920 \u0915\u093e\u0930\u094d\u092f\u093e\u0924\u094d\u092e\u0915 \u0914\u0930 \u0936\u093e\u0930\u0940\u0930\u093f\u0915 \u0938\u0902\u092c\u0902\u0927 \u0915\u094b \u0926\u0947\u0916\u0924\u0947 \u0939\u0941\u090f (\u0906\u092f\u0941\u0930\u094d\u0935\u0947\u0926 \u0915\u0940 \u092a\u0930\u0938\u094d\u092a\u0930 \u091c\u0941\u0921\u093c\u0940 <em>\u0938\u094d\u0930\u094b\u0924\u0938<\/em> \u0915\u0940 \u0905\u0935\u0927\u093e\u0930\u0923\u093e \u0915\u0947 \u0905\u0928\u0941\u0938\u093e\u0930), \u092a\u0941\u0928\u0930\u094d\u0928\u0935\u093e \u0915\u0947 \u091c\u094d\u091e\u093e\u0924 \u092f\u0915\u0943\u0924-\u0938\u0941\u0930\u0915\u094d\u0937\u093e\u0924\u094d\u092e\u0915 \u0917\u0941\u0923 \u0938\u092e\u0917\u094d\u0930 \u0935\u093f\u0937\u0939\u0930\u0923 \u0915\u094d\u0937\u092e\u0924\u093e \u092e\u0947\u0902 \u0938\u0941\u0927\u093e\u0930 \u0915\u0930\u0915\u0947 \u0905\u092a\u094d\u0930\u0924\u094d\u092f\u0915\u094d\u0937 \u0930\u0942\u092a \u0938\u0947 \u0917\u0941\u0930\u094d\u0926\u0947 \u0915\u0947 \u0938\u094d\u0935\u093e\u0938\u094d\u0925\u094d\u092f \u0915\u093e \u0938\u092e\u0930\u094d\u0925\u0928 \u0915\u0930\u0924\u0947 \u0939\u0948\u0902\u0964<\/li>\n<\/ul>\n\n<h2 class=\"wp-block-heading\">\u0928\u0948\u0926\u093e\u0928\u093f\u0915 \u200b\u200b\u0905\u0928\u0941\u092a\u094d\u0930\u092f\u094b\u0917 \u0914\u0930 \u090f\u0915\u0940\u0915\u0930\u0923<\/h2>\n<p>\u0906\u092f\u0941\u0930\u094d\u0935\u0947\u0926\u093f\u0915 \u0905\u092d\u094d\u092f\u093e\u0938 \u092e\u0947\u0902, \u092a\u0941\u0928\u0930\u094d\u0928\u0935\u093e \u0936\u093e\u092f\u0926 \u0939\u0940 \u0915\u092d\u0940 \u0905\u0915\u0947\u0932\u0947 \u0907\u0938\u094d\u0924\u0947\u092e\u093e\u0932 \u0915\u093f\u092f\u093e \u091c\u093e\u0924\u093e \u0939\u0948\u0964 \u0907\u0938\u0947 \u0905\u0915\u094d\u0938\u0930 \u092a\u0941\u0928\u0930\u094d\u0928\u0935\u093e\u0926\u093f \u0915\u093e\u0937\u093e\u092f\u092e \u092f\u093e \u092a\u0941\u0928\u0930\u094d\u0928\u0935\u093e\u0926\u093f \u0917\u0941\u0917\u094d\u0917\u0941\u0932\u0941 \u091c\u0948\u0938\u0947 \u091c\u091f\u093f\u0932 \u092f\u094b\u0917\u094b\u0902 \u092e\u0947\u0902 \u0936\u093e\u092e\u093f\u0932 \u0915\u093f\u092f\u093e \u091c\u093e\u0924\u093e \u0939\u0948, \u091c\u0939\u093e\u0902 \u0905\u0926\u0930\u0915 (<em>\u0936\u0941\u0902\u0920\u0940<\/em>), \u0915\u093e\u0932\u0940 \u092e\u093f\u0930\u094d\u091a (<em>\u092e\u0930\u093f\u091a<\/em>), \u0932\u0902\u092c\u0940 \u092e\u093f\u0930\u094d\u091a (<em>\u092a\u093f\u092a\u094d\u092a\u0932\u0940<\/em>), \u0939\u0932\u094d\u0926\u0940 (<em>\u0939\u0930\u093f\u0926\u094d\u0930\u093e<\/em>), \u0914\u0930 \u0924\u094d\u0930\u093f\u092b\u0932\u093e \u091c\u0948\u0938\u0940 \u0905\u0928\u094d\u092f \u091c\u0921\u093c\u0940-\u092c\u0942\u091f\u093f\u092f\u094b\u0902 \u0926\u094d\u0935\u093e\u0930\u093e \u0907\u0938\u0915\u0947 \u0917\u0941\u0923\u094b\u0902 \u0915\u094b \u0938\u0939\u0915\u094d\u0930\u093f\u092f\u093e\u0924\u094d\u092e\u0915 \u0930\u0942\u092a \u0938\u0947 \u092c\u0922\u093c\u093e\u092f\u093e \u091c\u093e\u0924\u093e \u0939\u0948\u0964 \u0907\u0938 \u092a\u0949\u0932\u0940\u0939\u0930\u094d\u092c\u0932 \u0926\u0943\u0937\u094d\u091f\u093f\u0915\u094b\u0923 \u0915\u093e \u0909\u0926\u094d\u0926\u0947\u0936\u094d\u092f \u0917\u0941\u0930\u094d\u0926\u0947 \u0915\u0947 \u0935\u093f\u0915\u093e\u0930\u094b\u0902 \u0915\u0940 \u092c\u0939\u0941\u0915\u094d\u0930\u093f\u092f\u093e\u0924\u094d\u092e\u0915 \u092a\u094d\u0930\u0915\u0943\u0924\u093f \u0914\u0930 \u0935\u094d\u092f\u0915\u094d\u0924\u093f\u0917\u0924 \u0938\u0902\u0935\u0948\u0927\u093e\u0928\u093f\u0915 \u0906\u0935\u0936\u094d\u092f\u0915\u0924\u093e\u0913\u0902 (\u092a\u094d\u0930\u0915\u0943\u0924\u093f) \u0915\u094b \u0938\u0902\u092c\u094b\u0927\u093f\u0924 \u0915\u0930\u0928\u093e \u0939\u0948\u0964<\/p>\n<p>\u0916\u0941\u0930\u093e\u0915 \u0914\u0930 \u0924\u0948\u092f\u093e\u0930\u0940 \u0930\u094b\u0917\u0940 \u0915\u0940 \u0926\u094b\u0937 \u0905\u0938\u0902\u0924\u0941\u0932\u0928, \u0938\u094d\u0925\u093f\u0924\u093f \u0915\u0940 \u0917\u0902\u092d\u0940\u0930\u0924\u093e \u0914\u0930 \u0905\u0928\u094d\u092f \u0938\u0939-\u0930\u0941\u0917\u094d\u0923\u0924\u093e\u0913\u0902 \u0915\u0940 \u0909\u092a\u0938\u094d\u0925\u093f\u0924\u093f \u0915\u0947 \u0906\u0927\u093e\u0930 \u092a\u0930 \u0938\u093e\u0935\u0927\u093e\u0928\u0940\u092a\u0942\u0930\u094d\u0935\u0915 \u0928\u093f\u0930\u094d\u0927\u093e\u0930\u093f\u0924 \u0915\u0940 \u091c\u093e\u0924\u0940 \u0939\u0948\u0964 \u0909\u0926\u093e\u0939\u0930\u0923 \u0915\u0947 \u0932\u093f\u090f, \u092e\u0939\u0924\u094d\u0935\u092a\u0942\u0930\u094d\u0923 \u090f\u0921\u093f\u092e\u093e \u0915\u0947 \u0938\u093e\u0925 \u0915\u092b-\u092a\u094d\u0930\u092e\u0941\u0916 \u092a\u094d\u0930\u0938\u094d\u0924\u0941\u0924\u093f \u092e\u0947\u0902, \u0907\u0938\u0915\u0947 \u0939\u0932\u094d\u0915\u0947, \u0924\u0947\u091c \u0915\u093e\u0930\u094d\u0930\u0935\u093e\u0908 \u0915\u0947 \u0932\u093f\u090f \u090f\u0915 \u0915\u093e\u0922\u093c\u093e (\u0915\u093e\u0937\u093e\u092f\u092e) \u0915\u094b \u092a\u094d\u0930\u093e\u0925\u092e\u093f\u0915\u0924\u093e \u0926\u0940 \u091c\u093e \u0938\u0915\u0924\u0940 \u0939\u0948\u0964 \u0935\u093e\u0924 \u0935\u093f\u0915\u0943\u0924\u093f \u0914\u0930 \u0926\u0930\u094d\u0926 \u0938\u0947 \u091c\u0941\u0921\u093c\u0947 \u092e\u093e\u092e\u0932\u094b\u0902 \u092e\u0947\u0902, \u0917\u0941\u0917\u094d\u0917\u0941\u0932\u0941 \u0915\u094b \u0936\u093e\u092e\u093f\u0932 \u0915\u0930\u0928\u0947 \u0935\u093e\u0932\u0947 \u092f\u094b\u0917\u094b\u0902 \u0915\u094b \u0909\u0928\u0915\u0947 \u0917\u0939\u0930\u0947 \u090a\u0924\u0915 \u092a\u094d\u0930\u0935\u0947\u0936 \u0914\u0930 \u0938\u0942\u091c\u0928-\u0930\u094b\u0927\u0940 \u092a\u094d\u0930\u092d\u093e\u0935\u094b\u0902 \u0915\u0947 \u0932\u093f\u090f \u091a\u0941\u0928\u093e \u091c\u093e \u0938\u0915\u0924\u093e \u0939\u0948\u0964<\/p>\n\n<div class=\"kr-protocol-box\">\n  <h3>\u092a\u0941\u0928\u0930\u094d\u0928\u0935\u093e \u0917\u0941\u0930\u094d\u0926\u093e \u0938\u0939\u093e\u092f\u0924\u093e \u092a\u094d\u0930\u094b\u091f\u094b\u0915\u0949\u0932 (\u0909\u0926\u093e\u0939\u0930\u0923\u093e\u0924\u094d\u092e\u0915)<\/h3>\n  <ol>\n    <li><strong>\u092e\u0942\u0932\u094d\u092f\u093e\u0902\u0915\u0928:<\/strong> \u0906\u092f\u0941\u0930\u094d\u0935\u0947\u0926\u093f\u0915 \u0938\u093f\u0926\u094d\u0927\u093e\u0902\u0924\u094b\u0902 \u0915\u093e \u0909\u092a\u092f\u094b\u0917 \u0915\u0930\u0915\u0947 \u0935\u094d\u092f\u0915\u094d\u0924\u093f\u0917\u0924 \u092a\u094d\u0930\u0915\u0943\u0924\u093f \u0914\u0930 \u0935\u093f\u0915\u0943\u0924\u093f (\u0938\u0902\u0935\u0948\u0927\u093e\u0928\u093f\u0915 \u092a\u094d\u0930\u0915\u093e\u0930 \u0914\u0930 \u0935\u0930\u094d\u0924\u092e\u093e\u0928 \u0905\u0938\u0902\u0924\u0941\u0932\u0928) \u0915\u093e \u0928\u093f\u0930\u094d\u0927\u093e\u0930\u0923 \u0915\u0930\u0947\u0902\u0964 \u0917\u0941\u0930\u094d\u0926\u0947 \u0915\u0947 \u0915\u093e\u0930\u094d\u092f \u092e\u093e\u0930\u094d\u0915\u0930\u094b\u0902 (\u091c\u0948\u0938\u0947, \u091c\u0940\u090f\u092b\u0906\u0930, \u0915\u094d\u0930\u093f\u090f\u091f\u093f\u0928\u093f\u0928, \u092c\u0940\u092f\u0942\u090f\u0928) \u0914\u0930 \u0926\u094d\u0930\u0935 \u0938\u0902\u0924\u0941\u0932\u0928 \u0915\u0940 \u0938\u094d\u0925\u093f\u0924\u093f (\u090f\u0921\u093f\u092e\u093e, \u092e\u0942\u0924\u094d\u0930 \u0909\u0924\u094d\u092a\u093e\u0926\u0928) \u0915\u093e \u0906\u0915\u0932\u0928 \u0915\u0930\u0947\u0902\u0964<\/li>\n    <li><strong>\u091c\u0921\u093c\u0940 \u092c\u0942\u091f\u0940 \u091a\u092f\u0928:<\/strong> \u092e\u0942\u0932\u094d\u092f\u093e\u0902\u0915\u0928 \u0915\u0947 \u0906\u0927\u093e\u0930 \u092a\u0930, \u0909\u092a\u092f\u0941\u0915\u094d\u0924 \u092a\u0941\u0928\u0930\u094d\u0928\u0935\u093e \u0938\u0942\u0924\u094d\u0930\u0940\u0915\u0930\u0923 (\u091c\u0948\u0938\u0947, \u092a\u0941\u0928\u0930\u094d\u0928\u0935\u093e\u0926\u093f \u0915\u093e\u0937\u093e\u092f\u092e, \u092a\u0941\u0928\u0930\u094d\u0928\u0935\u093e\u0926\u093f \u0917\u0941\u0917\u094d\u0917\u0941\u0932\u0941, \u092f\u093e \u092e\u093e\u0928\u0915\u0940\u0915\u0943\u0924 \u092a\u0941\u0928\u0930\u094d\u0928\u0935\u093e \u0905\u0930\u094d\u0915) \u0915\u093e \u091a\u092f\u0928 \u0915\u0930\u0947\u0902\u0964 \u0935\u093f\u0936\u093f\u0937\u094d\u091f \u0932\u0915\u094d\u0937\u0923\u094b\u0902 \u0914\u0930 \u0926\u094b\u0937 \u092d\u093e\u0917\u0940\u0926\u093e\u0930\u0940 \u0915\u0947 \u0906\u0927\u093e\u0930 \u092a\u0930 \u0938\u0939\u0915\u094d\u0930\u093f\u092f\u093e\u0924\u094d\u092e\u0915 \u091c\u0921\u093c\u0940-\u092c\u0942\u091f\u093f\u092f\u094b\u0902 \u092a\u0930 \u0935\u093f\u091a\u093e\u0930 \u0915\u0930\u0947\u0902\u0964<\/li>\n    <li><strong>\u0916\u0941\u0930\u093e\u0915 \u0914\u0930 \u092a\u094d\u0930\u0936\u093e\u0938\u0928:<\/strong> \u090f\u0915 \u0905\u0928\u0941\u092d\u0935\u0940 \u0906\u092f\u0941\u0930\u094d\u0935\u0947\u0926\u093f\u0915 \u091a\u093f\u0915\u093f\u0924\u094d\u0938\u0915 \u0926\u094d\u0935\u093e\u0930\u093e \u0928\u093f\u0930\u094d\u0927\u093e\u0930\u093f\u0924 \u0916\u0941\u0930\u093e\u0915 \u092a\u0930 \u091a\u0941\u0928\u0947 \u0917\u090f \u0938\u0942\u0924\u094d\u0930\u0940\u0915\u0930\u0923 \u0915\u094b \u092a\u094d\u0930\u0936\u093e\u0938\u093f\u0924 \u0915\u0930\u0947\u0902, \u0906\u092e\u0924\u094c\u0930 \u092a\u0930 \u092d\u094b\u091c\u0928 \u0938\u0947 \u092a\u0939\u0932\u0947 \u0926\u093f\u0928 \u092e\u0947\u0902 \u0926\u094b \u092c\u093e\u0930 10-30 \u092e\u093f\u0932\u0940 \u0915\u093e\u0937\u093e\u092f\u092e \u092f\u093e 1-2 \u0917\u0941\u0917\u094d\u0917\u0941\u0932\u0941 \u091f\u0948\u092c\u0932\u0947\u091f \u0915\u0940 \u0938\u0940\u092e\u093e \u092e\u0947\u0902\u0964 \u092a\u094d\u0930\u0924\u093f\u0915\u094d\u0930\u093f\u092f\u093e \u0915\u0947 \u0906\u0927\u093e\u0930 \u092a\u0930 \u0938\u092e\u093e\u092f\u094b\u091c\u093f\u0924 \u0915\u0930\u0947\u0902\u0964<\/li>\n    <li><strong>\u0906\u0939\u093e\u0930 \u0914\u0930 \u091c\u0940\u0935\u0928 \u0936\u0948\u0932\u0940 \u092e\u0947\u0902 \u0938\u0902\u0936\u094b\u0927\u0928:<\/strong> \u0928\u092e\u0915 \u0914\u0930 \u092a\u094d\u0930\u0938\u0902\u0938\u094d\u0915\u0943\u0924 \u0916\u093e\u0926\u094d\u092f \u092a\u0926\u093e\u0930\u094d\u0925\u094b\u0902 \u092e\u0947\u0902 \u0915\u092e \u0906\u0939\u093e\u0930 \u0915\u0940 \u0938\u093f\u092b\u093e\u0930\u093f\u0936 \u0915\u0930\u0947\u0902, \u0924\u093e\u091c\u0947, \u0906\u0938\u093e\u0928\u0940 \u0938\u0947 \u092a\u091a\u0928\u0947 \u092f\u094b\u0917\u094d\u092f \u0916\u093e\u0926\u094d\u092f \u092a\u0926\u093e\u0930\u094d\u0925\u094b\u0902 \u092a\u0930 \u091c\u094b\u0930 \u0926\u0947\u0902\u0964 \u092a\u0930\u094d\u092f\u093e\u092a\u094d\u0924 \u091c\u0932\u092f\u094b\u091c\u0928 (\u091c\u092c \u0924\u0915 \u0915\u093f \u0935\u093f\u092a\u0930\u0940\u0924 \u0938\u0902\u0915\u0947\u0924 \u0928 \u0939\u094b) \u0914\u0930 \u0928\u093f\u092f\u092e\u093f\u0924, \u092e\u0927\u094d\u092f\u092e \u0935\u094d\u092f\u093e\u092f\u093e\u092e \u0915\u094b \u092a\u094d\u0930\u094b\u0924\u094d\u0938\u093e\u0939\u093f\u0924 \u0915\u0930\u0947\u0902\u0964 \u0935\u093e\u0924-\u092c\u0922\u093c\u093e\u0928\u0947 \u0935\u093e\u0932\u0947 \u0915\u093e\u0930\u0915\u094b\u0902 \u0938\u0947 \u092c\u091a\u0947\u0902\u0964<\/li>\n    <li><strong>\u0928\u093f\u0917\u0930\u093e\u0928\u0940:<\/strong> \u0928\u093f\u092f\u092e\u093f\u0924 \u0930\u0942\u092a \u0938\u0947 \u092e\u0942\u0924\u094d\u0930 \u0909\u0924\u094d\u092a\u093e\u0926\u0928, \u090f\u0921\u093f\u092e\u093e \u0938\u094d\u0924\u0930 \u0914\u0930 \u092a\u094d\u0930\u093e\u0938\u0902\u0917\u093f\u0915 \u091c\u0948\u0935 \u0930\u093e\u0938\u093e\u092f\u0928\u093f\u0915 \u092e\u093e\u092a\u0926\u0902\u0921\u094b\u0902 \u0915\u0940 \u0928\u093f\u0917\u0930\u093e\u0928\u0940 \u0915\u0930\u0947\u0902\u0964 \u0906\u0935\u0936\u094d\u092f\u0915\u0924\u093e\u0928\u0941\u0938\u093e\u0930 \u0909\u092a\u091a\u093e\u0930 \u0938\u092e\u093e\u092f\u094b\u091c\u093f\u0924 \u0915\u0930\u0947\u0902\u0964<\/li>\n  <\/ol>\n  <p><em>\u0928\u094b\u091f: \u092f\u0939 \u090f\u0915 \u0938\u093e\u092e\u093e\u0928\u094d\u092f \u0926\u093f\u0936\u093e\u0928\u093f\u0930\u094d\u0926\u0947\u0936 \u0939\u0948\u0964 \u0935\u094d\u092f\u0915\u094d\u0924\u093f\u0917\u0924 \u0909\u092a\u091a\u093e\u0930 \u0915\u0947 \u0932\u093f\u090f \u0939\u092e\u0947\u0936\u093e \u090f\u0915 \u092f\u094b\u0917\u094d\u092f \u0906\u092f\u0941\u0930\u094d\u0935\u0947\u0926\u093f\u0915 \u091a\u093f\u0915\u093f\u0924\u094d\u0938\u0915 \u0938\u0947 \u0938\u0932\u093e\u0939 \u0932\u0947\u0902\u0964<\/em><\/p>\n<\/div>\n\n<div class=\"kr-calc-embed-callout\">\n  <p>\u0915\u094d\u092f\u093e \u0906\u092a \u0905\u092a\u0928\u0947 \u0905\u0926\u094d\u0935\u093f\u0924\u0940\u092f \u0906\u092f\u0941\u0930\u094d\u0935\u0947\u0926\u093f\u0915 \u0938\u0902\u0935\u093f\u0927\u093e\u0928 \u0915\u0947 \u092c\u093e\u0930\u0947 \u092e\u0947\u0902 \u0909\u0924\u094d\u0938\u0941\u0915 \u0939\u0948\u0902? \u0905\u092a\u0928\u0940 \u092a\u094d\u0930\u0915\u0943\u0924\u093f \u0915\u094b \u0938\u092e\u091d\u0928\u093e \u0935\u094d\u092f\u0915\u094d\u0924\u093f\u0917\u0924 \u0915\u0932\u094d\u092f\u093e\u0923 \u0930\u0923\u0928\u0940\u0924\u093f\u092f\u094b\u0902 \u0915\u093e \u092e\u093e\u0930\u094d\u0917\u0926\u0930\u094d\u0936\u0928 \u0915\u0930 \u0938\u0915\u0924\u093e \u0939\u0948\u0964 <a href=\"\/calculators\/dosha-diagnostic\/\" target=\"_blank\">\u0905\u092d\u0940 \u0906\u092f\u0941\u0930\u094d\u0935\u0947\u0926\u093f\u0915 \u0926\u094b\u0937 \u0928\u0948\u0926\u093e\u0928\u093f\u0915 \u200b\u200b\u0915\u094d\u0935\u093f\u091c\u093c \u0932\u0947\u0902\u0964<\/a><\/p>\n<\/div>\n\n<div class=\"kr-brief-sources\">\n  <h3>\u0938\u0902\u0926\u0930\u094d\u092d<\/h3>\n  <ul>\n    <li>\u091a\u0930\u0915 \u0938\u0902\u0939\u093f\u0924\u093e, \u0938\u0942\u0924\u094d\u0930\u0938\u094d\u0925\u093e\u0928, \u0905\u0927\u094d\u092f\u093e\u092f 27\u0964<\/li>\n    <li>\u0938\u0941\u0936\u094d\u0930\u0941\u0924 \u0938\u0902\u0939\u093f\u0924\u093e, \u0909\u0924\u094d\u0924\u0930 \u0924\u0902\u0924\u094d\u0930, \u0905\u0927\u094d\u092f\u093e\u092f 45\u0964<\/li>\n    <li>\u092c\u0943\u0939\u0924\u094d \u0928\u093f\u0918\u0902\u091f\u0941 \u0930\u0924\u094d\u0928\u093e\u0915\u0930\u0964<\/li>\n    <li>\u091c\u094b\u0936\u0940, \u0906\u0930., \u090f\u091f \u0905\u0932. (2013)\u0964 \u092d\u094b\u0930\u0939\u0935\u093f\u092f\u093e \u0921\u093f\u092b\u094d\u092f\u0942\u0938\u093e \u0915\u0940 \u0914\u0937\u0927\u0940\u092f \u0917\u0924\u093f\u0935\u093f\u0927\u093f\u092f\u093e\u0901: \u090f\u0915 \u0938\u092e\u0940\u0915\u094d\u0937\u093e\u0964 <em>\u0907\u0902\u091f\u0930\u0928\u0947\u0936\u0928\u0932 \u091c\u0930\u094d\u0928\u0932 \u0911\u092b \u092b\u093e\u0930\u094d\u092e\u093e\u0938\u094d\u092f\u0941\u091f\u093f\u0915\u0932 \u0938\u093e\u0907\u0902\u0938\u0947\u091c \u090f\u0902\u0921 \u0930\u093f\u0938\u0930\u094d\u091a<\/em>, 4(11), 4101-4110\u0964<\/li>\n    <li>\u0915\u0941\u092e\u093e\u0930, \u0935\u0940., \u090f\u091f \u0905\u0932. (2010)\u0964 \u092d\u094b\u0930\u0939\u0935\u093f\u092f\u093e \u0921\u093f\u092b\u094d\u092f\u0942\u0938\u093e \u091c\u0921\u093c \u0915\u0940 \u092e\u0942\u0924\u094d\u0930\u0935\u0930\u094d\u0927\u0915 \u0914\u0930 \u0938\u0942\u091c\u0928-\u0930\u094b\u0927\u0940 \u0917\u0924\u093f\u0935\u093f\u0927\u093f\u0964 <em>\u091c\u0930\u094d\u0928\u0932 \u0911\u092b \u090f\u0925\u094d\u0928\u094b\u092b\u093e\u0930\u094d\u092e\u093e\u0915\u094b\u0932\u0949\u091c\u0940<\/em>, 128(2), 435-439\u0964<\/li>\n    <li>\u0915\u0935\u093f\u0924\u093e, \u0915\u0947., \u090f\u091f \u0905\u0932. (2012)\u0964 \u092a\u094d\u0930\u092f\u094b\u0917\u093e\u0924\u094d\u092e\u0915 \u092e\u0949\u0921\u0932 \u092e\u0947\u0902 \u092d\u094b\u0930\u0939\u0935\u093f\u092f\u093e \u0921\u093f\u092b\u094d\u092f\u0942\u0938\u093e \u0932\u093f\u0928. \u0915\u0940 \u0938\u0942\u091c\u0928-\u0930\u094b\u0927\u0940 \u0914\u0930 \u090f\u0902\u091f\u0940\u0911\u0915\u094d\u0938\u0940\u0921\u0947\u0902\u091f \u0915\u094d\u0937\u092e\u0924\u093e\u0964 <em>\u091c\u0930\u094d\u0928\u0932 \u0911\u092b \u090f\u0925\u094d\u0928\u094b\u092b\u093e\u0930\u094d\u092e\u093e\u0915\u094b\u0932\u0949\u091c\u0940<\/em>, 143(1), 320-326\u0964<\/li>\n    <li>\u0938\u093e\u0939\u093e, \u090f\u0938., \u090f\u091f \u0905\u0932. (2015)\u0964 \u0938\u093f\u0938\u094d\u092a\u094d\u0932\u0948\u091f\u093f\u0928-\u092a\u094d\u0930\u0947\u0930\u093f\u0924 \u0917\u0941\u0930\u094d\u0926\u0947 \u0915\u0940 \u0935\u093f\u0937\u093e\u0915\u094d\u0924\u0924\u093e \u0915\u0947 \u0916\u093f\u0932\u093e\u092b \u092d\u094b\u0930\u0939\u0935\u093f\u092f\u093e \u0921\u093f\u092b\u094d\u092f\u0942\u0938\u093e \u0905\u0930\u094d\u0915 \u0915\u0947 \u090f\u0902\u091f\u0940\u0911\u0915\u094d\u0938\u0940\u0921\u0947\u0902\u091f \u0914\u0930 \u0928\u0947\u092b\u094d\u0930\u094b\u092a\u094d\u0930\u094b\u091f\u0947\u0915\u094d\u091f\u093f\u0935 \u092a\u094d\u0930\u092d\u093e\u0935\u0964 <em>\u091c\u0930\u094d\u0928\u0932 \u0911\u092b \u0915\u0949\u092e\u094d\u092a\u094d\u0932\u093f\u092e\u0947\u0902\u091f\u094d\u0930\u0940 \u090f\u0902\u0921 \u0907\u0902\u091f\u0940\u0917\u094d\u0930\u0947\u091f\u093f\u0935 \u092e\u0947\u0921\u093f\u0938\u093f\u0928<\/em>, 12(2), 139-147\u0964<\/li>\n  <\/ul>\n<\/div>\n<\/article>","_kr_takeaways_hi":"","footnotes":"","_kriyasya_companion_story_id":0,"_kriyasya_story_eligible":true,"_kriyasya_story_exclusion_reason":"","_kriyasya_world_key":"research","_kriyasya_world_bridge_enabled":false,"_kriyasya_audio_in_world":false},"categories":[15,65,62,63],"tags":[],"kriyasya_format":[32],"kriyasya_editorial_origin":[35],"kriyasya_content_kind":[39],"kriyasya_devotional_focus":[],"kriyasya_tradition":[],"kriyasya_language":[],"kriyasya_observance":[],"kriyasya_healing_modality":[],"class_list":["post-9697","post","type-post","status-publish","format-standard","hentry","category-ayurveda","category-research","category-science","category-wellness"],"_links":{"self":[{"href":"https:\/\/kriyasya.com\/pulse\/wp-json\/wp\/v2\/posts\/9697","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/kriyasya.com\/pulse\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/kriyasya.com\/pulse\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/kriyasya.com\/pulse\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/kriyasya.com\/pulse\/wp-json\/wp\/v2\/comments?post=9697"}],"version-history":[{"count":1,"href":"https:\/\/kriyasya.com\/pulse\/wp-json\/wp\/v2\/posts\/9697\/revisions"}],"predecessor-version":[{"id":10115,"href":"https:\/\/kriyasya.com\/pulse\/wp-json\/wp\/v2\/posts\/9697\/revisions\/10115"}],"wp:attachment":[{"href":"https:\/\/kriyasya.com\/pulse\/wp-json\/wp\/v2\/media?parent=9697"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/kriyasya.com\/pulse\/wp-json\/wp\/v2\/categories?post=9697"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/kriyasya.com\/pulse\/wp-json\/wp\/v2\/tags?post=9697"},{"taxonomy":"kriyasya_format","embeddable":true,"href":"https:\/\/kriyasya.com\/pulse\/wp-json\/wp\/v2\/kriyasya_format?post=9697"},{"taxonomy":"kriyasya_editorial_origin","embeddable":true,"href":"https:\/\/kriyasya.com\/pulse\/wp-json\/wp\/v2\/kriyasya_editorial_origin?post=9697"},{"taxonomy":"kriyasya_content_kind","embeddable":true,"href":"https:\/\/kriyasya.com\/pulse\/wp-json\/wp\/v2\/kriyasya_content_kind?post=9697"},{"taxonomy":"kriyasya_devotional_focus","embeddable":true,"href":"https:\/\/kriyasya.com\/pulse\/wp-json\/wp\/v2\/kriyasya_devotional_focus?post=9697"},{"taxonomy":"kriyasya_tradition","embeddable":true,"href":"https:\/\/kriyasya.com\/pulse\/wp-json\/wp\/v2\/kriyasya_tradition?post=9697"},{"taxonomy":"kriyasya_language","embeddable":true,"href":"https:\/\/kriyasya.com\/pulse\/wp-json\/wp\/v2\/kriyasya_language?post=9697"},{"taxonomy":"kriyasya_observance","embeddable":true,"href":"https:\/\/kriyasya.com\/pulse\/wp-json\/wp\/v2\/kriyasya_observance?post=9697"},{"taxonomy":"kriyasya_healing_modality","embeddable":true,"href":"https:\/\/kriyasya.com\/pulse\/wp-json\/wp\/v2\/kriyasya_healing_modality?post=9697"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}