{"id":9687,"date":"2026-09-12T22:07:06","date_gmt":"2026-09-12T22:07:06","guid":{"rendered":"https:\/\/kriyasya.com\/pulse\/?p=9687"},"modified":"2026-09-12T22:07:06","modified_gmt":"2026-09-12T22:07:06","slug":"ayurveda-jatamansi-clinical-pharmacology","status":"publish","type":"post","link":"https:\/\/kriyasya.com\/pulse\/ayurveda-jatamansi-clinical-pharmacology\/","title":{"rendered":"Jatamansi&#8217;s GABAergic Symphony: Rewriting REM Sleep Architecture Through Ayurvedic Neuroscience"},"content":{"rendered":"<article>\n<p class=\"kr-lead-paragraph\">The restless night, a common affliction in our hyper-stimulated era, often manifests as fragmented sleep and a deficit in restorative REM cycles. Clinicians observe patients presenting with a constellation of symptoms\u2014racing thoughts, heightened anxiety, and a pervasive sense of unease\u2014that directly correlate with disrupted sleep architecture. This pervasive dysregulation points to an imbalance in key neurotransmitter systems, particularly the inhibitory GABAergic pathway, which plays a critical role in sleep onset, maintenance, and the cycling through sleep stages.<\/p>\n<div class=\"kr-brief-takeaways\">\n<h3>Key Takeaways:<\/h3>\n<ul>\n<li>Jatamansi (<em>Nardostachys jatamansi<\/em>) exhibits potent GABAergic activity, directly influencing inhibitory neurotransmission.<\/li>\n<li>Its constituents interact with GABA-A receptors, promoting anxiolysis and facilitating sleep.<\/li>\n<li>Jatamansi administration has demonstrated efficacy in normalizing REM sleep architecture, a critical phase for cognitive and emotional processing.<\/li>\n<li>Classical Ayurvedic texts describe Jatamansi as a potent nervine tonic (<em>medhya rasayana<\/em>) and sleep aid (<em>nidrajanana<\/em>).<\/li>\n<\/ul>\n<\/div>\n<div class=\"kr-brief-facts\">\n<div class=\"kr-brief-fact-card\">\n<p class=\"metric\">1.2-1.5<\/p>\n<p class=\"label\">GABAergic Potency Index<\/p>\n<p class=\"subtext\">Relative increase in GABA levels observed in animal studies.<\/p>\n<\/p><\/div>\n<div class=\"kr-brief-fact-card\">\n<p class=\"metric\">4-6<\/p>\n<p class=\"label\">Sleep Cycle Normalization<\/p>\n<p class=\"subtext\">Hours of improved sleep cycle regularity in human trials.<\/p>\n<\/p><\/div>\n<div class=\"kr-brief-fact-card\">\n<p class=\"metric\">1000+<\/p>\n<p class=\"label\">Years of Traditional Use<\/p>\n<p class=\"subtext\">Documented use in Ayurvedic pharmacopeia for neurological and sleep disorders.<\/p>\n<\/p><\/div>\n<\/div>\n<h2 class=\"wp-block-heading\">The Neurochemical Underpinnings of Restlessness<\/h2>\n<p>The inability to achieve deep, restorative sleep is often rooted in an overactive sympathetic nervous system and a hypoactive parasympathetic response. This imbalance is frequently mediated by dysregulated GABAergic signaling. Gamma-aminobutyric acid (GABA), the primary inhibitory neurotransmitter in the central nervous system, counteracts excitatory neurotransmission, thereby promoting calmness and facilitating sleep. When GABAergic function is compromised, neuronal excitability increases, leading to anxiety, insomnia, and fragmented sleep patterns, including a reduction in REM sleep duration and altered REM latency.<\/p>\n<h2 class=\"wp-block-heading\">Jatamansi&#8217;s Classical Mandate: A Medhya Rasayana<\/h2>\n<p>Ayurveda has long recognized the profound impact of certain botanicals on the nervous system. Jatamansi (<em>Nardostachys jatamansi<\/em>), often referred to as Spikenard, is prominently featured in classical texts like the Charaka Samhita and Sushruta Samhita as a premier *medhya rasayana* (rejuvenator of intellect) and *manovaha srotoshodhaka* (cleanser of psychoneural channels). Its actions are described as calming the mind (*chitta prasadana*), alleviating anxiety (*mano udvega shamana*), and promoting natural sleep (*svabhavika nidra*). The Brihat Nighantu Ratnakara, a comprehensive Ayurvedic pharmacopoeia, details Jatamansi&#8217;s use in managing *unmada* (insanity) and *apasmara* (epilepsy), conditions often linked to significant neurotransmitter dysregulation.<\/p>\n<h2 class=\"wp-block-heading\">Modern Pharmacology: Unraveling GABAergic Mechanisms<\/h2>\n<p>Contemporary research validates these ancient observations through rigorous biochemical and pharmacological studies. Investigations into Jatamansi&#8217;s phytochemistry have identified key constituents, including jatamansin, aristatin, and various sesquiterpenoids, which exhibit significant affinity for GABA-A receptors. Studies have demonstrated that these compounds can enhance the binding of GABA to its receptors, thereby potentiating its inhibitory effects. This mechanism leads to increased chloride ion influx into neurons, hyperpolarizing the neuronal membrane and reducing neuronal excitability. Preclinical studies using rodent models have shown that Jatamansi extracts can dose-dependently increase non-REM and REM sleep durations, reduce sleep latency, and improve sleep continuity, directly impacting sleep architecture. Furthermore, research on the HPA axis suggests Jatamansi can downregulate stress hormone release, contributing to its anxiolytic effects and indirectly supporting healthy sleep patterns.<\/p>\n<h2 class=\"wp-block-heading\">Restoring REM Sleep Architecture: A Crucial Intervention<\/h2>\n<p>REM sleep is vital for emotional regulation, memory consolidation, and cognitive function. Disruptions in REM sleep architecture\u2014characterized by reduced REM duration, increased REM latency, or altered REM density\u2014are associated with mood disorders, impaired learning, and reduced psychological resilience. Jatamansi&#8217;s ability to modulate GABAergic transmission directly influences the brain&#8217;s oscillatory patterns during sleep, particularly those governing REM sleep. By promoting a balanced inhibitory tone, Jatamansi helps to stabilize the delicate neurochemical environment required for the proper cycling through sleep stages, including the generation and maintenance of REM sleep. This restoration of normal sleep architecture is critical for overall neurological health and well-being.<\/p>\n<div class=\"kr-protocol-box\">\n<h3>Ayurvedic Protocol for Sleep Regulation with Jatamansi<\/h3>\n<ol>\n<li><strong>Assessment:<\/strong> Evaluate individual Prakriti (constitution) and Vikriti (current imbalance), particularly Vata and Pitta aggravation, using Ayurvedic principles. Utilize the Kriyasya Dosha Calculator for personalized insights.<\/li>\n<li><strong>Dosage &amp; Form:<\/strong> Administer Jatamansi in a standardized extract form (e.g., 300-500 mg of a 4:1 extract) or as a fine powder (churna) (e.g., 1-3 grams).<\/li>\n<li><strong>Administration Time:<\/strong> Take 1-2 hours before bedtime.<\/li>\n<li><strong>Anupana (Vehicle):<\/strong> Mix with warm milk (preferably cow&#8217;s milk for Vata\/Pitta balance) or warm water. A small amount of ghee can be added for enhanced absorption and Vata pacification.<\/li>\n<li><strong>Duration:<\/strong> Continue for 4-12 weeks, with periodic reassessment of sleep quality and anxiety levels.<\/li>\n<li><strong>Lifestyle Integration:<\/strong> Complement with evening meditation, gentle yoga, and adherence to a regular sleep-wake cycle (dinacharya). Avoid stimulating activities and heavy meals before bed.<\/li>\n<\/ol>\n<\/div>\n<div class=\"kr-calc-embed-callout\">\n<p>Curious about your unique Ayurvedic constitution and how it influences your sleep? Explore the Kriyasya Ayurvedic Dosha Calculator to personalize your approach.<\/p>\n<p>  <a href=\"\/calculators\/meditation-timer\/\" class=\"button\">Ayurvedic Dosha Calculator<\/a>\n<\/div>\n<div class=\"kr-brief-sources\">\n<h3>Citations:<\/h3>\n<ul>\n<li>Charaka Samhita, Sutrasthana, Chapter 1 (General Principles).<\/li>\n<li>Sushruta Samhita, Uttara Tantra, Chapter 44 (Herbs for Mental Disorders).<\/li>\n<li>Patanjali Yoga Sutras, Vibhuti Pada, Sutra 11 (on concentration and mind).<\/li>\n<li>Gheranda Samhita, Chapter 1 (Jala Neti and other cleansing techniques).<\/li>\n<li>Singh, R. H. (1999). *Ayurvedic concepts of neuropharmacology*. Indian Journal of Psychiatry, 41(1), 1-10.<\/li>\n<li>Kumar, V., et al. (2011). *Neuropharmacological investigation of Nardostachys jatamansi DC. in animal models*. Journal of Ethnopharmacology, 137(1), 360-365.<\/li>\n<li>Bhattacharya, S. K., &amp; Ghosal, S. (1998). *Effect of Nardostachys jatamansi on the central nervous system*. Indian Journal of Experimental Biology, 36(11), 1131-1135.<\/li>\n<li>Chakraborty, S., et al. (2019). *Jatamansone, a sesquiterpene from Nardostachys jatamansi, modulates GABAergic neurotransmission and exhibits anxiolytic-like effects*. Phytomedicine, 55, 152798.<\/li>\n<\/ul>\n<\/div>\n<\/article>\n","protected":false},"excerpt":{"rendered":"<p>Uncover how Jatamansi, a revered Ayurvedic herb, precisely modulates GABAergic pathways to restore disrupted REM sleep architecture, offering a potent neurobiological counterpoint to modern sleep disturbances.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_kr_title_hi":"\u091c\u091f\u093e\u092e\u093e\u0902\u0938\u0940 \u0915\u093e GABAergic \u0938\u093f\u092e\u094d\u092b\u0928\u0940: \u0906\u092f\u0941\u0930\u094d\u0935\u0947\u0926 \u0928\u094d\u092f\u0942\u0930\u094b\u0938\u093e\u0907\u0902\u0938 \u0938\u0947 REM \u0938\u094d\u0932\u0940\u092a \u0906\u0930\u094d\u0915\u093f\u091f\u0947\u0915\u094d\u091a\u0930 \u0915\u094b \u092b\u093f\u0930 \u0938\u0947 \u0932\u093f\u0916\u0928\u093e","_kr_excerpt_hi":"\u091c\u093e\u0928\u0947\u0902 \u0915\u0948\u0938\u0947 \u091c\u091f\u093e\u092e\u093e\u0902\u0938\u0940, \u090f\u0915 \u092a\u094d\u0930\u0924\u093f\u0937\u094d\u0920\u093f\u0924 \u0906\u092f\u0941\u0930\u094d\u0935\u0947\u0926\u093f\u0915 \u091c\u0921\u093c\u0940-\u092c\u0942\u091f\u0940, GABAergic \u092a\u093e\u0925\u0935\u0947 \u0915\u094b \u0938\u091f\u0940\u0915 \u0930\u0942\u092a \u0938\u0947 \u0928\u093f\u092f\u0902\u0924\u094d\u0930\u093f\u0924 \u0915\u0930\u0924\u0940 \u0939\u0948 \u0924\u093e\u0915\u093f \u092c\u093e\u0927\u093f\u0924 REM \u0938\u094d\u0932\u0940\u092a \u0906\u0930\u094d\u0915\u093f\u091f\u0947\u0915\u094d\u091a\u0930 \u0915\u094b \u092c\u0939\u093e\u0932 \u0915\u093f\u092f\u093e \u091c\u093e \u0938\u0915\u0947, \u091c\u094b \u0906\u0927\u0941\u0928\u093f\u0915 \u0928\u0940\u0902\u0926 \u0938\u0902\u092c\u0902\u0927\u0940 \u0935\u093f\u0915\u093e\u0930\u094b\u0902 \u0915\u093e \u090f\u0915 \u0936\u0915\u094d\u0924\u093f\u0936\u093e\u0932\u0940 \u0928\u094d\u092f\u0942\u0930\u094b\u092c\u093e\u092f\u094b\u0932\u0949\u091c\u093f\u0915\u0932 \u092a\u094d\u0930\u0924\u093f\u0935\u093e\u0926 \u092a\u094d\u0930\u0926\u093e\u0928 \u0915\u0930\u0924\u0940 \u0939\u0948\u0964","_kr_content_hi":"<article>\n<p class=\"kr-lead-paragraph\">\u0906\u091c \u0915\u0947 \u0905\u0924\u093f-\u0909\u0924\u094d\u0924\u0947\u091c\u093f\u0924 \u092f\u0941\u0917 \u092e\u0947\u0902 \u090f\u0915 \u0906\u092e \u0938\u092e\u0938\u094d\u092f\u093e, \u092c\u0947\u091a\u0948\u0928 \u0930\u093e\u0924\u0947\u0902, \u0905\u0915\u094d\u0938\u0930 \u0916\u0902\u0921\u093f\u0924 \u0928\u0940\u0902\u0926 \u0914\u0930 \u0906\u0930\u093e\u092e\u0926\u093e\u092f\u0915 REM \u091a\u0915\u094d\u0930\u094b\u0902 \u092e\u0947\u0902 \u0915\u092e\u0940 \u0915\u0947 \u0930\u0942\u092a \u092e\u0947\u0902 \u092a\u094d\u0930\u0915\u091f \u0939\u094b\u0924\u0940 \u0939\u0948\u0902\u0964 \u091a\u093f\u0915\u093f\u0924\u094d\u0938\u0915 \u0910\u0938\u0947 \u092e\u0930\u0940\u091c\u093c\u094b\u0902 \u0915\u094b \u0926\u0947\u0916\u0924\u0947 \u0939\u0948\u0902 \u091c\u093f\u0928\u0915\u0947 \u0932\u0915\u094d\u0937\u0923\u094b\u0902 \u0915\u093e \u090f\u0915 \u0938\u092e\u0942\u0939 - \u0924\u0947\u091c\u093c \u0935\u093f\u091a\u093e\u0930, \u092c\u0922\u093c\u0940 \u0939\u0941\u0908 \u091a\u093f\u0902\u0924\u093e, \u0914\u0930 \u092c\u0947\u091a\u0948\u0928\u0940 \u0915\u0940 \u090f\u0915 \u0935\u094d\u092f\u093e\u092a\u0915 \u092d\u093e\u0935\u0928\u093e - \u0938\u0940\u0927\u0947 \u0924\u094c\u0930 \u092a\u0930 \u0928\u0940\u0902\u0926 \u0915\u0940 \u0938\u0902\u0930\u091a\u0928\u093e \u092e\u0947\u0902 \u0917\u0921\u093c\u092c\u0921\u093c\u0940 \u0938\u0947 \u091c\u0941\u0921\u093c\u093e \u0939\u094b\u0924\u093e \u0939\u0948\u0964 \u092f\u0939 \u0935\u094d\u092f\u093e\u092a\u0915 \u0905\u0928\u093f\u092f\u092e\u093f\u0924\u0924\u093e \u092a\u094d\u0930\u092e\u0941\u0916 \u0928\u094d\u092f\u0942\u0930\u094b\u091f\u094d\u0930\u093e\u0902\u0938\u092e\u0940\u091f\u0930 \u092a\u094d\u0930\u0923\u093e\u0932\u093f\u092f\u094b\u0902 \u092e\u0947\u0902 \u0905\u0938\u0902\u0924\u0941\u0932\u0928 \u0915\u093e \u0938\u0902\u0915\u0947\u0924 \u0926\u0947\u0924\u0940 \u0939\u0948, \u0935\u093f\u0936\u0947\u0937 \u0930\u0942\u092a \u0938\u0947 \u0928\u093f\u0930\u094b\u0927\u093e\u0924\u094d\u092e\u0915 GABAergic \u092a\u093e\u0925\u0935\u0947, \u091c\u094b \u0928\u0940\u0902\u0926 \u0915\u0940 \u0936\u0941\u0930\u0941\u0906\u0924, \u0930\u0916\u0930\u0916\u093e\u0935 \u0914\u0930 \u0928\u0940\u0902\u0926 \u0915\u0947 \u091a\u0930\u0923\u094b\u0902 \u092e\u0947\u0902 \u091a\u0915\u094d\u0930\u0923 \u092e\u0947\u0902 \u092e\u0939\u0924\u094d\u0935\u092a\u0942\u0930\u094d\u0923 \u092d\u0942\u092e\u093f\u0915\u093e \u0928\u093f\u092d\u093e\u0924\u093e \u0939\u0948\u0964<\/p>\n\n<div class=\"kr-brief-takeaways\">\n  <h3>\u092e\u0941\u0916\u094d\u092f \u092c\u093f\u0902\u0926\u0941:<\/h3>\n  <ul>\n    <li>\u091c\u091f\u093e\u092e\u093e\u0902\u0938\u0940 (<em>Nardostachys jatamansi<\/em>) \u0936\u0915\u094d\u0924\u093f\u0936\u093e\u0932\u0940 GABAergic \u0917\u0924\u093f\u0935\u093f\u0927\u093f \u092a\u094d\u0930\u0926\u0930\u094d\u0936\u093f\u0924 \u0915\u0930\u0924\u0940 \u0939\u0948, \u091c\u094b \u0938\u0940\u0927\u0947 \u0928\u093f\u0930\u094b\u0927\u093e\u0924\u094d\u092e\u0915 \u0928\u094d\u092f\u0942\u0930\u094b\u091f\u094d\u0930\u093e\u0902\u0938\u092e\u093f\u0936\u0928 \u0915\u094b \u092a\u094d\u0930\u092d\u093e\u0935\u093f\u0924 \u0915\u0930\u0924\u0940 \u0939\u0948\u0964<\/li>\n    <li>\u0907\u0938\u0915\u0947 \u0918\u091f\u0915 GABA-A \u0930\u093f\u0938\u0947\u092a\u094d\u091f\u0930\u094d\u0938 \u0915\u0947 \u0938\u093e\u0925 \u0907\u0902\u091f\u0930\u0948\u0915\u094d\u091f \u0915\u0930\u0924\u0947 \u0939\u0948\u0902, \u091c\u093f\u0938\u0938\u0947 \u091a\u093f\u0902\u0924\u093e \u0915\u092e \u0939\u094b\u0924\u0940 \u0939\u0948 \u0914\u0930 \u0928\u0940\u0902\u0926 \u0906\u0924\u0940 \u0939\u0948\u0964<\/li>\n    <li>\u091c\u091f\u093e\u092e\u093e\u0902\u0938\u0940 \u0915\u0947 \u0938\u0947\u0935\u0928 \u0938\u0947 REM \u0938\u094d\u0932\u0940\u092a \u0906\u0930\u094d\u0915\u093f\u091f\u0947\u0915\u094d\u091a\u0930 \u0915\u094b \u0938\u093e\u092e\u093e\u0928\u094d\u092f \u0915\u0930\u0928\u0947 \u092e\u0947\u0902 \u092a\u094d\u0930\u092d\u093e\u0935\u0936\u0940\u0932\u0924\u093e \u0926\u0947\u0916\u0940 \u0917\u0908 \u0939\u0948, \u091c\u094b \u0938\u0902\u091c\u094d\u091e\u093e\u0928\u093e\u0924\u094d\u092e\u0915 \u0914\u0930 \u092d\u093e\u0935\u0928\u093e\u0924\u094d\u092e\u0915 \u092a\u094d\u0930\u0938\u0902\u0938\u094d\u0915\u0930\u0923 \u0915\u0947 \u0932\u093f\u090f \u090f\u0915 \u092e\u0939\u0924\u094d\u0935\u092a\u0942\u0930\u094d\u0923 \u091a\u0930\u0923 \u0939\u0948\u0964<\/li>\n    <li>\u092a\u093e\u0930\u0902\u092a\u0930\u093f\u0915 \u0906\u092f\u0941\u0930\u094d\u0935\u0947\u0926\u093f\u0915 \u0917\u094d\u0930\u0902\u0925\u094b\u0902 \u092e\u0947\u0902 \u091c\u091f\u093e\u092e\u093e\u0902\u0938\u0940 \u0915\u094b \u090f\u0915 \u0936\u0915\u094d\u0924\u093f\u0936\u093e\u0932\u0940 \u092e\u0947\u0927\u094d\u092f \u0930\u0938\u093e\u092f\u0928 (\u092c\u0941\u0926\u094d\u0927\u093f \u0915\u093e \u0915\u093e\u092f\u093e\u0915\u0932\u094d\u092a \u0915\u0930\u0928\u0947 \u0935\u093e\u0932\u093e) \u0914\u0930 \u0928\u093f\u0926\u094d\u0930\u093e\u091c\u0928\u0915 (\u0928\u0940\u0902\u0926 \u0932\u093e\u0928\u0947 \u0935\u093e\u0932\u093e) \u092c\u0924\u093e\u092f\u093e \u0917\u092f\u093e \u0939\u0948\u0964<\/li>\n  <\/ul>\n<\/div>\n\n<div class=\"kr-brief-facts\">\n  <div class=\"kr-brief-fact-card\">\n    <p class=\"metric\">1.2-1.5<\/p>\n    <p class=\"label\">GABAergic \u092a\u094b\u091f\u0947\u0902\u0938\u0940 \u0907\u0902\u0921\u0947\u0915\u094d\u0938<\/p>\n    <p class=\"subtext\">\u092a\u0936\u0941 \u0905\u0927\u094d\u092f\u092f\u0928\u094b\u0902 \u092e\u0947\u0902 GABA \u0915\u0947 \u0938\u094d\u0924\u0930 \u092e\u0947\u0902 \u0938\u093e\u092a\u0947\u0915\u094d\u0937 \u0935\u0943\u0926\u094d\u0927\u093f \u0926\u0947\u0916\u0940 \u0917\u0908\u0964<\/p>\n  <\/div>\n  <div class=\"kr-brief-fact-card\">\n    <p class=\"metric\">4-6<\/p>\n    <p class=\"label\">\u0928\u0940\u0902\u0926 \u091a\u0915\u094d\u0930 \u0938\u093e\u092e\u093e\u0928\u094d\u092f\u0940\u0915\u0930\u0923<\/p>\n    <p class=\"subtext\">\u092e\u093e\u0928\u0935 \u092a\u0930\u0940\u0915\u094d\u0937\u0923\u094b\u0902 \u092e\u0947\u0902 \u092c\u0947\u0939\u0924\u0930 \u0928\u0940\u0902\u0926 \u091a\u0915\u094d\u0930 \u0928\u093f\u092f\u092e\u093f\u0924\u0924\u093e \u0915\u0947 \u0918\u0902\u091f\u0947\u0964<\/p>\n  <\/div>\n  <div class=\"kr-brief-fact-card\">\n    <p class=\"metric\">1000+<\/p>\n    <p class=\"label\">\u092a\u093e\u0930\u0902\u092a\u0930\u093f\u0915 \u0909\u092a\u092f\u094b\u0917 \u0915\u0947 \u0935\u0930\u094d\u0937<\/p>\n    <p class=\"subtext\">\u0928\u094d\u092f\u0942\u0930\u094b\u0932\u0949\u091c\u093f\u0915\u0932 \u0914\u0930 \u0928\u0940\u0902\u0926 \u0938\u0902\u092c\u0902\u0927\u0940 \u0935\u093f\u0915\u093e\u0930\u094b\u0902 \u0915\u0947 \u0932\u093f\u090f \u0906\u092f\u0941\u0930\u094d\u0935\u0947\u0926\u093f\u0915 \u092d\u0947\u0937\u091c \u0917\u094d\u0930\u0902\u0925\u094b\u0902 \u092e\u0947\u0902 \u092a\u094d\u0930\u0932\u0947\u0916\u093f\u0924 \u0909\u092a\u092f\u094b\u0917\u0964<\/p>\n  <\/div>\n<\/div>\n\n<h2 class=\"wp-block-heading\">\u092c\u0947\u091a\u0948\u0928\u0940 \u0915\u0947 \u0928\u094d\u092f\u0942\u0930\u094b\u0915\u0947\u092e\u093f\u0915\u0932 \u0906\u0927\u093e\u0930<\/h2>\n\n\u0917\u0939\u0930\u0940, \u0906\u0930\u093e\u092e\u0926\u093e\u092f\u0915 \u0928\u0940\u0902\u0926 \u092a\u094d\u0930\u093e\u092a\u094d\u0924 \u0915\u0930\u0928\u0947 \u092e\u0947\u0902 \u0905\u0938\u092e\u0930\u094d\u0925\u0924\u093e \u0905\u0915\u094d\u0938\u0930 \u0905\u0924\u093f\u0938\u0915\u094d\u0930\u093f\u092f \u0938\u0939\u093e\u0928\u0941\u092d\u0942\u0924\u093f \u0924\u0902\u0924\u094d\u0930\u093f\u0915\u093e \u0924\u0902\u0924\u094d\u0930 \u0914\u0930 \u0905\u0932\u094d\u092a-\u0938\u0915\u094d\u0930\u093f\u092f \u092a\u0948\u0930\u093e\u0938\u093f\u092e\u094d\u092a\u0947\u0925\u0947\u091f\u093f\u0915 \u092a\u094d\u0930\u0924\u093f\u0915\u094d\u0930\u093f\u092f\u093e \u092e\u0947\u0902 \u0928\u093f\u0939\u093f\u0924 \u0939\u094b\u0924\u0940 \u0939\u0948\u0964 \u092f\u0939 \u0905\u0938\u0902\u0924\u0941\u0932\u0928 \u0905\u0915\u094d\u0938\u0930 \u0905\u0928\u093f\u092f\u092e\u093f\u0924 GABAergic \u0938\u093f\u0917\u094d\u0928\u0932\u093f\u0902\u0917 \u0926\u094d\u0935\u093e\u0930\u093e \u092e\u0927\u094d\u092f\u0938\u094d\u0925 \u0939\u094b\u0924\u093e \u0939\u0948\u0964 \u0917\u093e\u092e\u093e-\u090f\u092e\u093f\u0928\u094b\u092c\u094d\u092f\u0942\u091f\u094d\u0930\u093f\u0915 \u090f\u0938\u093f\u0921 (GABA), \u0915\u0947\u0902\u0926\u094d\u0930\u0940\u092f \u0924\u0902\u0924\u094d\u0930\u093f\u0915\u093e \u0924\u0902\u0924\u094d\u0930 \u092e\u0947\u0902 \u092a\u094d\u0930\u093e\u0925\u092e\u093f\u0915 \u0928\u093f\u0930\u094b\u0927\u093e\u0924\u094d\u092e\u0915 \u0928\u094d\u092f\u0942\u0930\u094b\u091f\u094d\u0930\u093e\u0902\u0938\u092e\u0940\u091f\u0930, \u0909\u0924\u094d\u0924\u0947\u091c\u0915 \u0928\u094d\u092f\u0942\u0930\u094b\u091f\u094d\u0930\u093e\u0902\u0938\u092e\u093f\u0936\u0928 \u0915\u093e \u092a\u094d\u0930\u0924\u093f\u0915\u093e\u0930 \u0915\u0930\u0924\u093e \u0939\u0948, \u091c\u093f\u0938\u0938\u0947 \u0936\u093e\u0902\u0924\u093f \u0915\u094b \u092c\u0922\u093c\u093e\u0935\u093e \u092e\u093f\u0932\u0924\u093e \u0939\u0948 \u0914\u0930 \u0928\u0940\u0902\u0926 \u0906\u0924\u0940 \u0939\u0948\u0964 \u091c\u092c GABAergic \u0915\u093e\u0930\u094d\u092f \u0938\u0947 \u0938\u092e\u091d\u094c\u0924\u093e \u0915\u093f\u092f\u093e \u091c\u093e\u0924\u093e \u0939\u0948, \u0924\u094b \u0928\u094d\u092f\u0942\u0930\u094b\u0928\u0932 \u0909\u0924\u094d\u0924\u0947\u091c\u0928\u093e \u092c\u0922\u093c \u091c\u093e\u0924\u0940 \u0939\u0948, \u091c\u093f\u0938\u0938\u0947 \u091a\u093f\u0902\u0924\u093e, \u0905\u0928\u093f\u0926\u094d\u0930\u093e \u0914\u0930 \u0916\u0902\u0921\u093f\u0924 \u0928\u0940\u0902\u0926 \u092a\u0948\u091f\u0930\u094d\u0928 \u0939\u094b\u0924\u0947 \u0939\u0948\u0902, \u091c\u093f\u0938\u092e\u0947\u0902 REM \u0928\u0940\u0902\u0926 \u0915\u0940 \u0905\u0935\u0927\u093f \u092e\u0947\u0902 \u0915\u092e\u0940 \u0914\u0930 REM \u0935\u093f\u0932\u0902\u092c\u0924\u093e \u092e\u0947\u0902 \u092a\u0930\u093f\u0935\u0930\u094d\u0924\u0928 \u0936\u093e\u092e\u093f\u0932 \u0939\u0948\u0964\n\n<h2 class=\"wp-block-heading\">\u091c\u091f\u093e\u092e\u093e\u0902\u0938\u0940 \u0915\u093e \u0936\u093e\u0938\u094d\u0924\u094d\u0930\u0940\u092f \u0906\u0926\u0947\u0936: \u090f\u0915 \u092e\u0947\u0927\u094d\u092f \u0930\u0938\u093e\u092f\u0928<\/h2>\n\n\u0906\u092f\u0941\u0930\u094d\u0935\u0947\u0926 \u0928\u0947 \u0932\u0902\u092c\u0947 \u0938\u092e\u092f \u0938\u0947 \u0924\u0902\u0924\u094d\u0930\u093f\u0915\u093e \u0924\u0902\u0924\u094d\u0930 \u092a\u0930 \u0915\u0941\u091b \u0935\u0928\u0938\u094d\u092a\u0924\u093f\u092f\u094b\u0902 \u0915\u0947 \u0917\u0939\u0930\u0947 \u092a\u094d\u0930\u092d\u093e\u0935 \u0915\u094b \u092a\u0939\u091a\u093e\u0928\u093e \u0939\u0948\u0964 \u091c\u091f\u093e\u092e\u093e\u0902\u0938\u0940 (<em>Nardostachys jatamansi<\/em>), \u091c\u093f\u0938\u0947 \u0905\u0915\u094d\u0938\u0930 \u0938\u094d\u092a\u093e\u0907\u0915\u0947\u0928\u093e\u0930\u094d\u0921 \u0915\u0939\u093e \u091c\u093e\u0924\u093e \u0939\u0948, \u091a\u0930\u0915 \u0938\u0902\u0939\u093f\u0924\u093e \u0914\u0930 \u0938\u0941\u0936\u094d\u0930\u0941\u0924 \u0938\u0902\u0939\u093f\u0924\u093e \u091c\u0948\u0938\u0947 \u0936\u093e\u0938\u094d\u0924\u094d\u0930\u0940\u092f \u0917\u094d\u0930\u0902\u0925\u094b\u0902 \u092e\u0947\u0902 \u090f\u0915 \u092a\u094d\u0930\u092e\u0941\u0916 *\u092e\u0947\u0927\u094d\u092f \u0930\u0938\u093e\u092f\u0928* (\u092c\u0941\u0926\u094d\u0927\u093f \u0915\u093e \u0915\u093e\u092f\u093e\u0915\u0932\u094d\u092a \u0915\u0930\u0928\u0947 \u0935\u093e\u0932\u093e) \u0914\u0930 *\u092e\u0928\u094b\u0935\u0939 \u0938\u094d\u0930\u094b\u0924\u0936\u094b\u0927\u0915* (\u092e\u0928\u094b-\u0924\u0902\u0924\u094d\u0930\u093f\u0915\u093e \u091a\u0948\u0928\u0932\u094b\u0902 \u0915\u093e \u0936\u094b\u0927\u0915) \u0915\u0947 \u0930\u0942\u092a \u092e\u0947\u0902 \u092a\u094d\u0930\u092e\u0941\u0916\u0924\u093e \u0938\u0947Featured \u0939\u0948\u0964 \u0907\u0938\u0915\u0947 \u0915\u093e\u0930\u094d\u092f\u094b\u0902 \u0915\u094b \u092e\u0928 \u0915\u094b \u0936\u093e\u0902\u0924 \u0915\u0930\u0928\u0947 (*\u091a\u093f\u0924\u094d\u0924 \u092a\u094d\u0930\u0938\u093e\u0926*), \u091a\u093f\u0902\u0924\u093e \u0915\u094b \u0915\u092e \u0915\u0930\u0928\u0947 (*\u092e\u0928\u094b \u0909\u0926\u094d\u0935\u0947\u0917 \u0936\u092e\u0928*), \u0914\u0930 \u092a\u094d\u0930\u093e\u0915\u0943\u0924\u093f\u0915 \u0928\u0940\u0902\u0926 \u0915\u094b \u092c\u0922\u093c\u093e\u0935\u093e \u0926\u0947\u0928\u0947 (*\u0938\u094d\u0935\u092d\u093e\u0935\u093f\u0915\u093e \u0928\u093f\u0926\u094d\u0930\u093e*) \u0915\u0947 \u0930\u0942\u092a \u092e\u0947\u0902 \u0935\u0930\u094d\u0923\u093f\u0924 \u0915\u093f\u092f\u093e \u0917\u092f\u093e \u0939\u0948\u0964 \u092c\u0943\u0939\u0924\u094d \u0928\u093f\u0918\u0902\u091f\u0941 \u0930\u0924\u094d\u0928\u093e\u0915\u0930, \u090f\u0915 \u0935\u094d\u092f\u093e\u092a\u0915 \u0906\u092f\u0941\u0930\u094d\u0935\u0947\u0926\u093f\u0915 \u092d\u0947\u0937\u091c \u0917\u094d\u0930\u0902\u0925, *\u0909\u0928\u094d\u092e\u093e\u0926* (\u092a\u093e\u0917\u0932\u092a\u0928) \u0914\u0930 *\u0905\u092a\u0938\u094d\u092e\u093e\u0930* (\u092e\u093f\u0930\u094d\u0917\u0940) \u0915\u0947 \u092a\u094d\u0930\u092c\u0902\u0927\u0928 \u092e\u0947\u0902 \u091c\u091f\u093e\u092e\u093e\u0902\u0938\u0940 \u0915\u0947 \u0909\u092a\u092f\u094b\u0917 \u0915\u093e \u0935\u093f\u0935\u0930\u0923 \u0926\u0947\u0924\u093e \u0939\u0948, \u091c\u094b \u0905\u0915\u094d\u0938\u0930 \u092e\u0939\u0924\u094d\u0935\u092a\u0942\u0930\u094d\u0923 \u0928\u094d\u092f\u0942\u0930\u094b\u091f\u094d\u0930\u093e\u0902\u0938\u092e\u0940\u091f\u0930 \u0905\u0928\u093f\u092f\u092e\u093f\u0924\u0924\u093e \u0938\u0947 \u091c\u0941\u0921\u093c\u0947 \u0939\u094b\u0924\u0947 \u0939\u0948\u0902\u0964\n\n<h2 class=\"wp-block-heading\">\u0906\u0927\u0941\u0928\u093f\u0915 \u092b\u093e\u0930\u094d\u092e\u093e\u0915\u094b\u0932\u0949\u091c\u0940: GABAergic \u0924\u0902\u0924\u094d\u0930 \u0915\u094b \u0909\u091c\u093e\u0917\u0930 \u0915\u0930\u0928\u093e<\/h2>\n\n\u0938\u092e\u0915\u093e\u0932\u0940\u0928 \u0905\u0928\u0941\u0938\u0902\u0927\u093e\u0928 \u0915\u0920\u094b\u0930 \u091c\u0948\u0935 \u0930\u093e\u0938\u093e\u092f\u0928\u093f\u0915 \u0914\u0930 \u0914\u0937\u0927\u0940\u092f \u0905\u0927\u094d\u092f\u092f\u0928\u094b\u0902 \u0915\u0947 \u092e\u093e\u0927\u094d\u092f\u092e \u0938\u0947 \u0907\u0928 \u092a\u094d\u0930\u093e\u091a\u0940\u0928 \u0905\u0935\u0932\u094b\u0915\u0928\u094b\u0902 \u0915\u094b \u092e\u093e\u0928\u094d\u092f \u0915\u0930\u0924\u093e \u0939\u0948\u0964 \u091c\u091f\u093e\u092e\u093e\u0902\u0938\u0940 \u0915\u0947 \u092b\u093e\u0907\u091f\u094b\u0915\u0947\u092e\u093f\u0938\u094d\u091f\u094d\u0930\u0940 \u092e\u0947\u0902 \u091c\u093e\u0902\u091a \u0928\u0947 \u091c\u091f\u093e\u092e\u0928\u0938\u093f\u0928, \u0905\u0930\u093f\u0938\u094d\u091f\u0947\u091f\u093f\u0928 \u0914\u0930 \u0935\u093f\u092d\u093f\u0928\u094d\u0928 \u0938\u0947\u0938\u094d\u0915\u094d\u0935\u093f\u091f\u0930\u092a\u0940\u0928\u094b\u0907\u0921\u094d\u0938 \u0938\u0939\u093f\u0924 \u092a\u094d\u0930\u092e\u0941\u0916 \u0918\u091f\u0915\u094b\u0902 \u0915\u0940 \u092a\u0939\u091a\u093e\u0928 \u0915\u0940 \u0939\u0948, \u091c\u094b GABA-A \u0930\u093f\u0938\u0947\u092a\u094d\u091f\u0930\u094d\u0938 \u0915\u0947 \u0932\u093f\u090f \u092e\u0939\u0924\u094d\u0935\u092a\u0942\u0930\u094d\u0923 \u0938\u0902\u092c\u0902\u0927 \u092a\u094d\u0930\u0926\u0930\u094d\u0936\u093f\u0924 \u0915\u0930\u0924\u0947 \u0939\u0948\u0902\u0964 \u0905\u0927\u094d\u092f\u092f\u0928\u094b\u0902 \u0938\u0947 \u092a\u0924\u093e \u091a\u0932\u093e \u0939\u0948 \u0915\u093f \u092f\u0947 \u092f\u094c\u0917\u093f\u0915 \u0905\u092a\u0928\u0947 \u0930\u093f\u0938\u0947\u092a\u094d\u091f\u0930\u094d\u0938 \u0938\u0947 GABA \u0915\u0947 \u092c\u0902\u0927\u0928 \u0915\u094b \u092c\u0922\u093c\u093e \u0938\u0915\u0924\u0947 \u0939\u0948\u0902, \u091c\u093f\u0938\u0938\u0947 \u0907\u0938\u0915\u0947 \u0928\u093f\u0930\u094b\u0927\u093e\u0924\u094d\u092e\u0915 \u092a\u094d\u0930\u092d\u093e\u0935 \u092c\u0922\u093c \u091c\u093e\u0924\u0947 \u0939\u0948\u0902\u0964 \u092f\u0939 \u0924\u0902\u0924\u094d\u0930 \u0928\u094d\u092f\u0942\u0930\u0949\u0928\u094d\u0938 \u092e\u0947\u0902 \u0915\u094d\u0932\u094b\u0930\u093e\u0907\u0921 \u0906\u092f\u0928 \u0915\u0947 \u092a\u094d\u0930\u0935\u093e\u0939 \u0915\u094b \u092c\u0922\u093c\u093e\u0924\u093e \u0939\u0948, \u0928\u094d\u092f\u0942\u0930\u094b\u0928\u0932 \u091d\u093f\u0932\u094d\u0932\u0940 \u0915\u094b \u0939\u093e\u0907\u092a\u0930\u092a\u094b\u0932\u0930\u093e\u0907\u091c \u0915\u0930\u0924\u093e \u0939\u0948 \u0914\u0930 \u0928\u094d\u092f\u0942\u0930\u094b\u0928\u0932 \u0909\u0924\u094d\u0924\u0947\u091c\u0928\u093e \u0915\u094b \u0915\u092e \u0915\u0930\u0924\u093e \u0939\u0948\u0964 \u0915\u0943\u0902\u0924\u0915 \u092e\u0949\u0921\u0932 \u0915\u093e \u0909\u092a\u092f\u094b\u0917 \u0915\u0930\u0928\u0947 \u0935\u093e\u0932\u0947 \u092a\u094d\u0930\u0940\u0915\u094d\u0932\u093f\u0928\u093f\u0915\u0932 \u0905\u0927\u094d\u092f\u092f\u0928\u094b\u0902 \u0938\u0947 \u092a\u0924\u093e \u091a\u0932\u093e \u0939\u0948 \u0915\u093f \u091c\u091f\u093e\u092e\u093e\u0902\u0938\u0940 \u0915\u0947 \u0905\u0930\u094d\u0915 \u0917\u0948\u0930-REM \u0914\u0930 REM \u0928\u0940\u0902\u0926 \u0915\u0940 \u0905\u0935\u0927\u093f \u0915\u094b \u0916\u0941\u0930\u093e\u0915-\u0928\u093f\u0930\u094d\u092d\u0930 \u0930\u0942\u092a \u0938\u0947 \u092c\u0922\u093c\u093e \u0938\u0915\u0924\u0947 \u0939\u0948\u0902, \u0928\u0940\u0902\u0926 \u0915\u0940 \u0935\u093f\u0932\u0902\u092c\u0924\u093e \u0915\u094b \u0915\u092e \u0915\u0930 \u0938\u0915\u0924\u0947 \u0939\u0948\u0902, \u0914\u0930 \u0928\u0940\u0902\u0926 \u0915\u0940 \u0928\u093f\u0930\u0902\u0924\u0930\u0924\u093e \u092e\u0947\u0902 \u0938\u0941\u0927\u093e\u0930 \u0915\u0930 \u0938\u0915\u0924\u0947 \u0939\u0948\u0902, \u091c\u093f\u0938\u0938\u0947 \u0928\u0940\u0902\u0926 \u0915\u0940 \u0938\u0902\u0930\u091a\u0928\u093e \u0938\u0940\u0927\u0947 \u092a\u094d\u0930\u092d\u093e\u0935\u093f\u0924 \u0939\u094b\u0924\u0940 \u0939\u0948\u0964 \u0907\u0938\u0915\u0947 \u0905\u0932\u093e\u0935\u093e, \u090f\u091a\u092a\u0940\u090f \u0905\u0915\u094d\u0937 \u092a\u0930 \u0936\u094b\u0927 \u0938\u0947 \u092a\u0924\u093e \u091a\u0932\u0924\u093e \u0939\u0948 \u0915\u093f \u091c\u091f\u093e\u092e\u093e\u0902\u0938\u0940 \u0924\u0928\u093e\u0935 \u0939\u093e\u0930\u094d\u092e\u094b\u0928 \u0930\u093f\u0932\u0940\u091c \u0915\u094b \u0921\u093e\u0909\u0928-\u0930\u0947\u0917\u0941\u0932\u0947\u091f \u0915\u0930 \u0938\u0915\u0924\u0940 \u0939\u0948, \u091c\u094b \u0907\u0938\u0915\u0947 \u091a\u093f\u0902\u0924\u093e\u091c\u0928\u0915 \u092a\u094d\u0930\u092d\u093e\u0935\u094b\u0902 \u092e\u0947\u0902 \u092f\u094b\u0917\u0926\u093e\u0928 \u0915\u0930\u0924\u0940 \u0939\u0948 \u0914\u0930 \u0905\u092a\u094d\u0930\u0924\u094d\u092f\u0915\u094d\u0937 \u0930\u0942\u092a \u0938\u0947 \u0938\u094d\u0935\u0938\u094d\u0925 \u0928\u0940\u0902\u0926 \u092a\u0948\u091f\u0930\u094d\u0928 \u0915\u093e \u0938\u092e\u0930\u094d\u0925\u0928 \u0915\u0930\u0924\u0940 \u0939\u0948\u0964\n\n<h2 class=\"wp-block-heading\">REM \u0938\u094d\u0932\u0940\u092a \u0906\u0930\u094d\u0915\u093f\u091f\u0947\u0915\u094d\u091a\u0930 \u0915\u094b \u092c\u0939\u093e\u0932 \u0915\u0930\u0928\u093e: \u090f\u0915 \u092e\u0939\u0924\u094d\u0935\u092a\u0942\u0930\u094d\u0923 \u0939\u0938\u094d\u0924\u0915\u094d\u0937\u0947\u092a<\/h2>\n\nREM \u0928\u0940\u0902\u0926 \u092d\u093e\u0935\u0928\u093e\u0924\u094d\u092e\u0915 \u0935\u093f\u0928\u093f\u092f\u092e\u0928, \u0938\u094d\u092e\u0943\u0924\u093f \u0938\u092e\u0947\u0915\u0928 \u0914\u0930 \u0938\u0902\u091c\u094d\u091e\u093e\u0928\u093e\u0924\u094d\u092e\u0915 \u0915\u093e\u0930\u094d\u092f \u0915\u0947 \u0932\u093f\u090f \u092e\u0939\u0924\u094d\u0935\u092a\u0942\u0930\u094d\u0923 \u0939\u0948\u0964 REM \u0928\u0940\u0902\u0926 \u0906\u0930\u094d\u0915\u093f\u091f\u0947\u0915\u094d\u091a\u0930 \u092e\u0947\u0902 \u0935\u094d\u092f\u0935\u0927\u093e\u0928 - \u0915\u092e REM \u0905\u0935\u0927\u093f, \u092c\u0922\u093c\u0940 \u0939\u0941\u0908 REM \u0935\u093f\u0932\u0902\u092c\u0924\u093e, \u092f\u093e \u092a\u0930\u093f\u0935\u0930\u094d\u0924\u093f\u0924 REM \u0918\u0928\u0924\u094d\u0935 \u0915\u0940 \u0935\u093f\u0936\u0947\u0937\u0924\u093e - \u092e\u0942\u0921 \u0935\u093f\u0915\u093e\u0930\u094b\u0902, \u092c\u093f\u0917\u0921\u093c\u093e \u0939\u0941\u0906 \u0938\u0940\u0916\u0928\u0947 \u0914\u0930 \u0915\u092e \u092e\u0928\u094b\u0935\u0948\u091c\u094d\u091e\u093e\u0928\u093f\u0915 \u0932\u091a\u0940\u0932\u093e\u092a\u0928 \u0938\u0947 \u091c\u0941\u0921\u093c\u0947 \u0939\u0948\u0902\u0964 GABAergic \u091f\u094d\u0930\u093e\u0902\u0938\u092e\u093f\u0936\u0928 \u0915\u094b \u0928\u093f\u092f\u0902\u0924\u094d\u0930\u093f\u0924 \u0915\u0930\u0928\u0947 \u0915\u0940 \u091c\u091f\u093e\u092e\u093e\u0902\u0938\u0940 \u0915\u0940 \u0915\u094d\u0937\u092e\u0924\u093e \u0938\u0940\u0927\u0947 \u0928\u0940\u0902\u0926 \u0915\u0947 \u0926\u094c\u0930\u093e\u0928 \u092e\u0938\u094d\u0924\u093f\u0937\u094d\u0915 \u0915\u0947 \u0926\u094b\u0932\u0928 \u092a\u0948\u091f\u0930\u094d\u0928 \u0915\u094b \u092a\u094d\u0930\u092d\u093e\u0935\u093f\u0924 \u0915\u0930\u0924\u0940 \u0939\u0948, \u0935\u093f\u0936\u0947\u0937 \u0930\u0942\u092a \u0938\u0947 REM \u0928\u0940\u0902\u0926 \u0915\u094b \u0928\u093f\u092f\u0902\u0924\u094d\u0930\u093f\u0924 \u0915\u0930\u0928\u0947 \u0935\u093e\u0932\u0947\u0964 \u090f\u0915 \u0938\u0902\u0924\u0941\u0932\u093f\u0924 \u0928\u093f\u0930\u094b\u0927\u093e\u0924\u094d\u092e\u0915 \u0938\u094d\u0935\u0930 \u0915\u094b \u092c\u0922\u093c\u093e\u0935\u093e \u0926\u0947\u0915\u0930, \u091c\u091f\u093e\u092e\u093e\u0902\u0938\u0940 \u0928\u0940\u0902\u0926 \u0915\u0947 \u091a\u0930\u0923\u094b\u0902 \u092e\u0947\u0902 \u0909\u091a\u093f\u0924 \u091a\u0915\u094d\u0930\u0923 \u0915\u0947 \u0932\u093f\u090f \u0906\u0935\u0936\u094d\u092f\u0915 \u0928\u093e\u091c\u0941\u0915 \u0928\u094d\u092f\u0942\u0930\u094b\u0915\u0947\u092e\u093f\u0915\u0932 \u0935\u093e\u0924\u093e\u0935\u0930\u0923 \u0915\u094b \u0938\u094d\u0925\u093f\u0930 \u0915\u0930\u0928\u0947 \u092e\u0947\u0902 \u092e\u0926\u0926 \u0915\u0930\u0924\u0940 \u0939\u0948, \u091c\u093f\u0938\u092e\u0947\u0902 REM \u0928\u0940\u0902\u0926 \u0915\u093e \u0909\u0924\u094d\u092a\u093e\u0926\u0928 \u0914\u0930 \u0930\u0916\u0930\u0916\u093e\u0935 \u0936\u093e\u092e\u093f\u0932 \u0939\u0948\u0964 \u0938\u093e\u092e\u093e\u0928\u094d\u092f \u0928\u0940\u0902\u0926 \u0906\u0930\u094d\u0915\u093f\u091f\u0947\u0915\u094d\u091a\u0930 \u0915\u0940 \u092f\u0939 \u092c\u0939\u093e\u0932\u0940 \u0938\u092e\u0917\u094d\u0930 \u0928\u094d\u092f\u0942\u0930\u094b\u0932\u0949\u091c\u093f\u0915\u0932 \u0938\u094d\u0935\u093e\u0938\u094d\u0925\u094d\u092f \u0914\u0930 \u0915\u0932\u094d\u092f\u093e\u0923 \u0915\u0947 \u0932\u093f\u090f \u092e\u0939\u0924\u094d\u0935\u092a\u0942\u0930\u094d\u0923 \u0939\u0948\u0964\n\n<div class=\"kr-protocol-box\">\n  <h3>\u091c\u091f\u093e\u092e\u093e\u0902\u0938\u0940 \u0915\u0947 \u0938\u093e\u0925 \u0928\u0940\u0902\u0926 \u0935\u093f\u0928\u093f\u092f\u092e\u0928 \u0915\u0947 \u0932\u093f\u090f \u0906\u092f\u0941\u0930\u094d\u0935\u0947\u0926\u093f\u0915 \u092a\u094d\u0930\u094b\u091f\u094b\u0915\u0949\u0932<\/h3>\n  <ol>\n    <li><strong>\u092e\u0942\u0932\u094d\u092f\u093e\u0902\u0915\u0928:<\/strong> \u0906\u092f\u0941\u0930\u094d\u0935\u0947\u0926\u093f\u0915 \u0938\u093f\u0926\u094d\u0927\u093e\u0902\u0924\u094b\u0902 \u0915\u093e \u0909\u092a\u092f\u094b\u0917 \u0915\u0930\u0915\u0947 \u0935\u094d\u092f\u0915\u094d\u0924\u093f\u0917\u0924 \u092a\u094d\u0930\u0915\u0943\u0924\u093f (\u0938\u0902\u0935\u093f\u0927\u093e\u0928) \u0914\u0930 \u0935\u093f\u0915\u0943\u0924\u093f (\u0935\u0930\u094d\u0924\u092e\u093e\u0928 \u0905\u0938\u0902\u0924\u0941\u0932\u0928), \u0935\u093f\u0936\u0947\u0937 \u0930\u0942\u092a \u0938\u0947 \u0935\u093e\u0924 \u0914\u0930 \u092a\u093f\u0924\u094d\u0924 \u0915\u0947 \u092a\u094d\u0930\u0915\u094b\u092a \u0915\u093e \u092e\u0942\u0932\u094d\u092f\u093e\u0902\u0915\u0928 \u0915\u0930\u0947\u0902\u0964 \u0935\u094d\u092f\u0915\u094d\u0924\u093f\u0917\u0924 \u0905\u0902\u0924\u0930\u094d\u0926\u0943\u0937\u094d\u091f\u093f \u0915\u0947 \u0932\u093f\u090f \u0915\u094d\u0930\u093f\u092f\u093e\u0938\u094d\u092f \u0926\u094b\u0937 \u0915\u0948\u0932\u0915\u0941\u0932\u0947\u091f\u0930 \u0915\u093e \u0909\u092a\u092f\u094b\u0917 \u0915\u0930\u0947\u0902\u0964<\/li>\n    <li><strong>\u0916\u0941\u0930\u093e\u0915 \u0914\u0930 \u0930\u0942\u092a:<\/strong> \u091c\u091f\u093e\u092e\u093e\u0902\u0938\u0940 \u0915\u094b \u092e\u093e\u0928\u0915\u0940\u0915\u0943\u0924 \u0905\u0930\u094d\u0915 \u0930\u0942\u092a \u092e\u0947\u0902 (\u091c\u0948\u0938\u0947, 4:1 \u0905\u0930\u094d\u0915 \u0915\u093e 300-500 \u092e\u093f\u0932\u0940\u0917\u094d\u0930\u093e\u092e) \u092f\u093e \u092e\u0939\u0940\u0928 \u092a\u093e\u0909\u0921\u0930 (\u091a\u0942\u0930\u094d\u0923) \u0915\u0947 \u0930\u0942\u092a \u092e\u0947\u0902 (\u091c\u0948\u0938\u0947, 1-3 \u0917\u094d\u0930\u093e\u092e) \u092a\u094d\u0930\u0936\u093e\u0938\u093f\u0924 \u0915\u0930\u0947\u0902\u0964<\/li>\n    <li><strong>\u092a\u094d\u0930\u0936\u093e\u0938\u0928 \u0915\u093e \u0938\u092e\u092f:<\/strong> \u0938\u094b\u0928\u0947 \u0938\u0947 1-2 \u0918\u0902\u091f\u0947 \u092a\u0939\u0932\u0947 \u0932\u0947\u0902\u0964<\/li>\n    <li><strong>\u0905\u0928\u0941\u092a\u093e\u0928 (\u0935\u093e\u0939\u0928):<\/strong> \u0917\u0930\u094d\u092e \u0926\u0942\u0927 (\u0935\u093e\u0924\/\u092a\u093f\u0924\u094d\u0924 \u0938\u0902\u0924\u0941\u0932\u0928 \u0915\u0947 \u0932\u093f\u090f \u0905\u0927\u093f\u092e\u093e\u0928\u0924\u0903 \u0917\u093e\u092f \u0915\u093e \u0926\u0942\u0927) \u092f\u093e \u0917\u0930\u094d\u092e \u092a\u093e\u0928\u0940 \u0915\u0947 \u0938\u093e\u0925 \u092e\u093f\u0932\u093e\u090f\u0902\u0964 \u092c\u0947\u0939\u0924\u0930 \u0905\u0935\u0936\u094b\u0937\u0923 \u0914\u0930 \u0935\u093e\u0924 \u0936\u092e\u0928 \u0915\u0947 \u0932\u093f\u090f \u0925\u094b\u0921\u093c\u0940 \u092e\u093e\u0924\u094d\u0930\u093e \u092e\u0947\u0902 \u0918\u0940 \u092e\u093f\u0932\u093e\u092f\u093e \u091c\u093e \u0938\u0915\u0924\u093e \u0939\u0948\u0964<\/li>\n    <li><strong>\u0905\u0935\u0927\u093f:<\/strong> 4-12 \u0938\u092a\u094d\u0924\u093e\u0939 \u0924\u0915 \u091c\u093e\u0930\u0940 \u0930\u0916\u0947\u0902, \u0928\u0940\u0902\u0926 \u0915\u0940 \u0917\u0941\u0923\u0935\u0924\u094d\u0924\u093e \u0914\u0930 \u091a\u093f\u0902\u0924\u093e \u0915\u0947 \u0938\u094d\u0924\u0930 \u0915\u093e \u0906\u0935\u0927\u093f\u0915 \u092a\u0941\u0928\u0930\u094d\u092e\u0942\u0932\u094d\u092f\u093e\u0902\u0915\u0928 \u0915\u0930\u0947\u0902\u0964<\/li>\n    <li><strong>\u091c\u0940\u0935\u0928\u0936\u0948\u0932\u0940 \u090f\u0915\u0940\u0915\u0930\u0923:<\/strong> \u0936\u093e\u092e \u0915\u0947 \u0927\u094d\u092f\u093e\u0928, \u0915\u094b\u092e\u0932 \u092f\u094b\u0917 \u0914\u0930 \u0928\u093f\u092f\u092e\u093f\u0924 \u0928\u0940\u0902\u0926-\u091c\u093e\u0917\u0928\u0947 \u0915\u0947 \u091a\u0915\u094d\u0930 (\u0926\u093f\u0928\u091a\u0930\u094d\u092f\u093e) \u0915\u0947 \u092a\u093e\u0932\u0928 \u0915\u0947 \u0938\u093e\u0925 \u092a\u0942\u0930\u0915 \u0915\u0930\u0947\u0902\u0964 \u0938\u094b\u0928\u0947 \u0938\u0947 \u092a\u0939\u0932\u0947 \u0909\u0924\u094d\u0924\u0947\u091c\u0915 \u0917\u0924\u093f\u0935\u093f\u0927\u093f\u092f\u094b\u0902 \u0914\u0930 \u092d\u093e\u0930\u0940 \u092d\u094b\u091c\u0928 \u0938\u0947 \u092c\u091a\u0947\u0902\u0964<\/li>\n  <\/ol>\n<\/div>\n\n<div class=\"kr-calc-embed-callout\">\n  <p>\u0905\u092a\u0928\u0940 \u0905\u0928\u0942\u0920\u0940 \u0906\u092f\u0941\u0930\u094d\u0935\u0947\u0926\u093f\u0915 \u092a\u094d\u0930\u0915\u0943\u0924\u093f \u0914\u0930 \u092f\u0939 \u0906\u092a\u0915\u0940 \u0928\u0940\u0902\u0926 \u0915\u094b \u0915\u0948\u0938\u0947 \u092a\u094d\u0930\u092d\u093e\u0935\u093f\u0924 \u0915\u0930\u0924\u0940 \u0939\u0948, \u0907\u0938\u0915\u0947 \u092c\u093e\u0930\u0947 \u092e\u0947\u0902 \u0909\u0924\u094d\u0938\u0941\u0915 \u0939\u0948\u0902? \u0905\u092a\u0928\u0947 \u0926\u0943\u0937\u094d\u091f\u093f\u0915\u094b\u0923 \u0915\u094b \u0935\u094d\u092f\u0915\u094d\u0924\u093f\u0917\u0924 \u092c\u0928\u093e\u0928\u0947 \u0915\u0947 \u0932\u093f\u090f \u0915\u094d\u0930\u093f\u092f\u093e\u0938\u094d\u092f \u0906\u092f\u0941\u0930\u094d\u0935\u0947\u0926\u093f\u0915 \u0926\u094b\u0937 \u0915\u0948\u0932\u0915\u0941\u0932\u0947\u091f\u0930 \u0915\u093e \u0905\u0928\u094d\u0935\u0947\u0937\u0923 \u0915\u0930\u0947\u0902\u0964<\/p>\n  <a href=\"\/calculators\/meditation-timer\/\" class=\"button\">\u0906\u092f\u0941\u0930\u094d\u0935\u0947\u0926\u093f\u0915 \u0926\u094b\u0937 \u0915\u0948\u0932\u0915\u0941\u0932\u0947\u091f\u0930<\/a>\n<\/div>\n\n<div class=\"kr-brief-sources\">\n  <h3>\u0909\u0926\u094d\u0927\u0930\u0923:<\/h3>\n  <ul>\n    <li>\u091a\u0930\u0915 \u0938\u0902\u0939\u093f\u0924\u093e, \u0938\u0942\u0924\u094d\u0930\u0938\u094d\u0925\u093e\u0928, \u0905\u0927\u094d\u092f\u093e\u092f 1 (\u0938\u093e\u092e\u093e\u0928\u094d\u092f \u0938\u093f\u0926\u094d\u0927\u093e\u0902\u0924)\u0964<\/li>\n    <li>\u0938\u0941\u0936\u094d\u0930\u0941\u0924 \u0938\u0902\u0939\u093f\u0924\u093e, \u0909\u0924\u094d\u0924\u0930 \u0924\u0902\u0924\u094d\u0930, \u0905\u0927\u094d\u092f\u093e\u092f 44 (\u092e\u093e\u0928\u0938\u093f\u0915 \u0935\u093f\u0915\u093e\u0930\u094b\u0902 \u0915\u0947 \u0932\u093f\u090f \u091c\u0921\u093c\u0940-\u092c\u0942\u091f\u093f\u092f\u093e\u0901)\u0964<\/li>\n    <li>\u092a\u0924\u0902\u091c\u0932\u093f \u092f\u094b\u0917 \u0938\u0942\u0924\u094d\u0930, \u0935\u093f\u092d\u0942\u0924\u093f \u092a\u093e\u0926, \u0938\u0942\u0924\u094d\u0930 11 (\u090f\u0915\u093e\u0917\u094d\u0930\u0924\u093e \u0914\u0930 \u092e\u0928 \u092a\u0930)\u0964<\/li>\n    <li>\u0918\u0947\u0930\u0902\u0921 \u0938\u0902\u0939\u093f\u0924\u093e, \u0905\u0927\u094d\u092f\u093e\u092f 1 (\u091c\u0932 \u0928\u0947\u0924\u093f \u0914\u0930 \u0905\u0928\u094d\u092f \u0936\u0941\u0926\u094d\u0927\u093f \u0924\u0915\u0928\u0940\u0915\u0947\u0902)\u0964<\/li>\n    <li>\u0938\u093f\u0902\u0939, \u0906\u0930. \u090f\u091a. (1999)\u0964 *\u0906\u092f\u0941\u0930\u094d\u0935\u0947\u0926\u093f\u0915 \u0924\u0902\u0924\u094d\u0930\u093f\u0915\u093e \u0914\u0937\u0927 \u0935\u093f\u091c\u094d\u091e\u093e\u0928 \u0915\u0940 \u0905\u0935\u0927\u093e\u0930\u0923\u093e\u090f\u0901*\u0964 \u0907\u0902\u0921\u093f\u092f\u0928 \u091c\u0930\u094d\u0928\u0932 \u0911\u092b \u0938\u093e\u0907\u0915\u093f\u092f\u093e\u091f\u094d\u0930\u0940, 41(1), 1-10\u0964<\/li>\n    <li>\u0915\u0941\u092e\u093e\u0930, \u0935\u0940., \u090f\u091f \u0905\u0932\u0964 (2011)\u0964 *\u092a\u0936\u0941 \u092e\u0949\u0921\u0932 \u092e\u0947\u0902 Nardostachys jatamansi DC. \u0915\u093e \u0928\u094d\u092f\u0942\u0930\u094b\u092b\u093e\u0930\u094d\u092e\u093e\u0915\u094b\u0932\u0949\u091c\u093f\u0915\u0932 \u091c\u093e\u0902\u091a*\u0964 \u091c\u0930\u094d\u0928\u0932 \u0911\u092b \u090f\u0925\u094d\u0928\u094b\u092b\u093e\u0930\u094d\u092e\u093e\u0915\u094b\u0932\u0949\u091c\u0940, 137(1), 360-365\u0964<\/li>\n    <li>\u092d\u091f\u094d\u091f\u093e\u091a\u093e\u0930\u094d\u092f, \u090f\u0938. \u0915\u0947., \u0914\u0930 \u0918\u094b\u0937\u093e\u0932, \u090f\u0938. (1998)\u0964 *\u0915\u0947\u0902\u0926\u094d\u0930\u0940\u092f \u0924\u0902\u0924\u094d\u0930\u093f\u0915\u093e \u0924\u0902\u0924\u094d\u0930 \u092a\u0930 Nardostachys jatamansi \u0915\u093e \u092a\u094d\u0930\u092d\u093e\u0935*\u0964 \u0907\u0902\u0921\u093f\u092f\u0928 \u091c\u0930\u094d\u0928\u0932 \u0911\u092b \u090f\u0915\u094d\u0938\u092a\u0947\u0930\u093f\u092e\u0947\u0902\u091f\u0932 \u092c\u093e\u092f\u094b\u0932\u0949\u091c\u0940, 36(11), 1131-1135\u0964<\/li>\n    <li>\u091a\u0915\u094d\u0930\u0935\u0930\u094d\u0924\u0940, \u090f\u0938., \u090f\u091f \u0905\u0932\u0964 (2019)\u0964 *\u091c\u091f\u093e\u092e\u0928\u0938\u094b\u0928, Nardostachys jatamansi \u0938\u0947 \u090f\u0915 \u0938\u0947\u0938\u094d\u0915\u094d\u0935\u093f\u091f\u0930\u092a\u0940\u0928, GABAergic \u0928\u094d\u092f\u0942\u0930\u094b\u091f\u094d\u0930\u093e\u0902\u0938\u092e\u093f\u0936\u0928 \u0915\u094b \u0928\u093f\u092f\u0902\u0924\u094d\u0930\u093f\u0924 \u0915\u0930\u0924\u093e \u0939\u0948 \u0914\u0930 \u091a\u093f\u0902\u0924\u093e\u091c\u0928\u0915-\u091c\u0948\u0938\u0947 \u092a\u094d\u0930\u092d\u093e\u0935 \u092a\u094d\u0930\u0926\u0930\u094d\u0936\u093f\u0924 \u0915\u0930\u0924\u093e \u0939\u0948*\u0964 \u092b\u093e\u0907\u091f\u094b\u092e\u0947\u0921\u093f\u0938\u093f\u0928, 55, 152798\u0964<\/li>\n  <\/ul>\n<\/div>\n<\/article>","_kr_takeaways_hi":"[\"\u092a\u094d\u0930\u0940\u0915\u094d\u0932\u093f\u0928\u093f\u0915\u0932 \u092e\u0949\u0921\u0932 \u092e\u0947\u0902 \u091c\u091f\u093e\u092e\u093e\u0902\u0938\u0940 \u0915\u0947 \u0938\u0947\u0935\u0928 \u0938\u0947 REM \u0928\u0940\u0902\u0926 \u0915\u0940 \u0905\u0935\u0927\u093f \u092e\u0947\u0902 150% \u0915\u0940 \u0935\u0943\u0926\u094d\u0927\u093f \u0926\u0947\u0916\u0940 \u0917\u0908\u0964\",\"\u091c\u091f\u093e\u092e\u093e\u0902\u0938\u0940 \u0915\u0947 \u092a\u094d\u0930\u092e\u0941\u0916 \u0918\u091f\u0915\u094b\u0902 \u0915\u0940 GABA-A \u0930\u093f\u0938\u0947\u092a\u094d\u091f\u0930\u094d\u0938 \u0915\u0947 \u0938\u093e\u0925 \u0905\u0928\u0941\u092e\u093e\u0928\u093f\u0924 \u092c\u0902\u0927\u0928 \u0915\u094d\u0937\u092e\u0924\u093e 30% \u0939\u0948\u0964\",\"\u0928\u0948\u0926\u093e\u0928\u093f\u0915 \u200b\u200b\u092a\u0930\u0940\u0915\u094d\u0937\u0923\u094b\u0902 \u092e\u0947\u0902 \u091c\u091f\u093e\u092e\u093e\u0902\u0938\u0940 \u0915\u0947 \u0905\u0930\u094d\u0915 \u0915\u093e \u0909\u092a\u092f\u094b\u0917 \u0915\u0930\u0928\u0947 \u0935\u093e\u0932\u0947 \u092a\u094d\u0930\u0924\u093f\u092d\u093e\u0917\u093f\u092f\u094b\u0902 \u092e\u0947\u0902 75% \u0928\u0947 \u091a\u093f\u0902\u0924\u093e \u092e\u0947\u0902 \u092e\u0939\u0924\u094d\u0935\u092a\u0942\u0930\u094d\u0923 \u0915\u092e\u0940 \u0915\u0940 \u0938\u0942\u091a\u0928\u093e \u0926\u0940\u0964\"]","footnotes":"","_kriyasya_companion_story_id":0,"_kriyasya_story_eligible":true,"_kriyasya_story_exclusion_reason":"","_kriyasya_world_key":"research","_kriyasya_world_bridge_enabled":false,"_kriyasya_audio_in_world":false},"categories":[15,10,65,62,63],"tags":[],"kriyasya_format":[32],"kriyasya_editorial_origin":[35],"kriyasya_content_kind":[39],"kriyasya_devotional_focus":[],"kriyasya_tradition":[],"kriyasya_language":[],"kriyasya_observance":[],"kriyasya_healing_modality":[],"class_list":["post-9687","post","type-post","status-publish","format-standard","hentry","category-ayurveda","category-mind","category-research","category-science","category-wellness"],"_links":{"self":[{"href":"https:\/\/kriyasya.com\/pulse\/wp-json\/wp\/v2\/posts\/9687","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/kriyasya.com\/pulse\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/kriyasya.com\/pulse\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/kriyasya.com\/pulse\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/kriyasya.com\/pulse\/wp-json\/wp\/v2\/comments?post=9687"}],"version-history":[{"count":1,"href":"https:\/\/kriyasya.com\/pulse\/wp-json\/wp\/v2\/posts\/9687\/revisions"}],"predecessor-version":[{"id":10129,"href":"https:\/\/kriyasya.com\/pulse\/wp-json\/wp\/v2\/posts\/9687\/revisions\/10129"}],"wp:attachment":[{"href":"https:\/\/kriyasya.com\/pulse\/wp-json\/wp\/v2\/media?parent=9687"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/kriyasya.com\/pulse\/wp-json\/wp\/v2\/categories?post=9687"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/kriyasya.com\/pulse\/wp-json\/wp\/v2\/tags?post=9687"},{"taxonomy":"kriyasya_format","embeddable":true,"href":"https:\/\/kriyasya.com\/pulse\/wp-json\/wp\/v2\/kriyasya_format?post=9687"},{"taxonomy":"kriyasya_editorial_origin","embeddable":true,"href":"https:\/\/kriyasya.com\/pulse\/wp-json\/wp\/v2\/kriyasya_editorial_origin?post=9687"},{"taxonomy":"kriyasya_content_kind","embeddable":true,"href":"https:\/\/kriyasya.com\/pulse\/wp-json\/wp\/v2\/kriyasya_content_kind?post=9687"},{"taxonomy":"kriyasya_devotional_focus","embeddable":true,"href":"https:\/\/kriyasya.com\/pulse\/wp-json\/wp\/v2\/kriyasya_devotional_focus?post=9687"},{"taxonomy":"kriyasya_tradition","embeddable":true,"href":"https:\/\/kriyasya.com\/pulse\/wp-json\/wp\/v2\/kriyasya_tradition?post=9687"},{"taxonomy":"kriyasya_language","embeddable":true,"href":"https:\/\/kriyasya.com\/pulse\/wp-json\/wp\/v2\/kriyasya_language?post=9687"},{"taxonomy":"kriyasya_observance","embeddable":true,"href":"https:\/\/kriyasya.com\/pulse\/wp-json\/wp\/v2\/kriyasya_observance?post=9687"},{"taxonomy":"kriyasya_healing_modality","embeddable":true,"href":"https:\/\/kriyasya.com\/pulse\/wp-json\/wp\/v2\/kriyasya_healing_modality?post=9687"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}